About: A Test for Constant Fatality Rate of an Emerging Epidemic: With Applications to Severe Acute Respiratory Syndrome in Hong Kong and Beijing

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A Test for Constant Fatality Rate of an Emerging Epidemic: With Applications to Severe Acute Respiratory Syndrome in Hong Kong and Beijing
Creator	Xu, Ying Yip, P Lau, E Lam, K Deshpande, J Naik-Nimbalkar, U
Source	PMC
abstract	summary The etiology, pathogenesis, and prognosis for a newly emerging disease are generally unknown to clinicians. Effective interventions and treatments at the earliest possible times are warranted to suppress the fatality of the disease to a minimum, and inappropriate treatments should be abolished. In this situation, the ability to extract most information out of the data available is critical so that important decisions can be made. Ineffectiveness of the treatment can be reflected by a constant fatality over time while effective treatment normally leads to a decreasing fatality rate. A statistical test for constant fatality over time is proposed in this article. The proposed statistic is shown to converge to a Brownian motion asymptotically under the null hypothesis. With the special features of the Brownian motion, we are able to analyze the first passage time distribution based on a sequential tests approach. This allows the null hypothesis of constant fatality rate to be rejected at the earliest possible time when adequate statistical evidence accumulates. Simulation studies show that the performance of the proposed test is good and it is extremely sensitive in picking up decreasing fatality rate. The proposed test is applied to the severe acute respiratory syndrome data in Hong Kong and Beijing.
has issue date	2007-11-28(xsd:dateTime)
bibo:doi	10.1111/j.1541-0420.2007.00935.x
has license	no-cc
sha1sum (hex)	61a94a9a3c38ebffc0bc3b5d2dde84f299a27569
schema:url	https://doi.org/10.1111/j.1541-0420.2007.00935.x
resource representing a document's title	A Test for Constant Fatality Rate of an Emerging Epidemic: With Applications to Severe Acute Respiratory Syndrome in Hong Kong and Beijing
has PubMed Central identifier	PMC7188335
schema:publication	Biometrics
resource representing a document's body	covid:61a94a9a3c38ebffc0bc3b5d2dde84f299a27569#body_text
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