About: Characterization of a novel, low-cost, scalable vaporized hydrogen peroxide system for sterilization of N95 respirators and other COVID-19 related personal protective equipment.

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About: Characterization of a novel, low-cost, scalable vaporized hydrogen peroxide system for sterilization of N95 respirators and other COVID-19 related personal protective equipment. Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Characterization of a novel, low-cost, scalable vaporized hydrogen peroxide system for sterilization of N95 respirators and other COVID-19 related personal protective equipment.
Creator	Patterson, John Wallace, David Smith, Tyler Abbaszadegan, Morteza Alum, Absar Chang, Josh Chowdhury, Abhik Dave, Nikhil Ewell, Clinton Herckes, Pierre Kozicki, Michael Naufel, Mark Pascavis, Katie Zhang, Zhaobo Forzani, Erica Mora, S
Source	MedRxiv
abstract	Due to the virulence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen responsible for the respiratory disease termed COVID-19, there has been a significant increase in demand for surgical masks and N95 respirators in medical clinics as well as within communities operating during the COVID-19 epidemic. Thus, community members, business owners, and even medical personnel have resorted to alternative methods for sterilizing face coverings and N95 respirators for reuse. While significant work has shown that vaporized hydrogen peroxide (VHP) can be used to sterilize N95 respirators, the cost and installation time for these sterilization systems limit their accessibility. To this end, we have designed and constructed a novel, cost-effective, and scalable VHP system that can be used to sterilize N95 respirators and other face coverings for clinical and community applications. N95 respirators inoculated with P22 bacteriophage showed a greater than 6-log10 reduction in viral load when sterilized in the VHP system for one 60-minute cycle. Further, N95 respirators treated with 20 cycles in this VHP system showed comparable filtration efficiency to untreated N95 respirators in a 50 to 200 nanometer particulate challenge filtration test. While a 23% average increase in water droplet roll-off time was observed for N95 respirators treated with 5 cycles in the sterilization, no breakdown in fluid resistance was detected. These data suggest that our VHP system is effective in sterilizing N95 respirators and other polypropylene masks for reuse. Relating to the present epidemic, deployment of this system reduces the risk of COVID-19 community transmission while conserving monetary resources otherwise spent on the continuous purchase of disposable N95 respirators and other face coverings. In summary, this novel, scientifically validated sterilization system can be easily built at a low cost and implemented in a wide range of settings.
has issue date	2020-06-26(xsd:dateTime)
bibo:doi	10.1101/2020.06.24.20139436
has license	medrxiv
sha1sum (hex)	5f06ba1241585ab2bbae1a9a065f1c34651ea509
schema:url	https://doi.org/10.1101/2020.06.24.20139436
resource representing a document's title	Characterization of a novel, low-cost, scalable vaporized hydrogen peroxide system for sterilization of N95 respirators and other COVID-19 related personal protective equipment.
resource representing a document's body	covid:5f06ba1241585ab2bbae1a9a065f1c34651ea509#body_text
is schema:about of	named entity 'COVID-19' named entity 'scalable' named entity 'Characterization' named entity 'vaporized hydrogen peroxide' named entity 'personal protective equipment' named entity 'medRxiv' named entity 'ppm' named entity 'respirator' named entity 'medRxiv' named entity 'N95' named entity 'fiberglass' named entity 'inhalation' named entity 'sterilization' named entity 'N95' named entity 'VHP' named entity 'VHP' named entity 'hydrogen peroxide' named entity 'nanoparticle' named entity 'SARS-CoV-2' named entity 'solid waste' named entity 'ambient pressure' named entity 'preprint' named entity 'bacteria' named entity 'sterilization' named entity 'recommended exposure limit' named entity 'test tube' named entity 'VHP' named entity 'VHP' named entity 'VHP' named entity 'N95' named entity 'preprint' named entity 'watch glass' named entity 'SARS-CoV-2' named entity 'vacuum level' named entity 'partial pressure' named entity 'PPE' named entity 'COVID-19 pandemic' named entity 'preprint' named entity 'bacteriophage' named entity 'N95' named entity 'preprint' named entity 'gas phase' named entity 'aqueous solution' named entity 'ethylene oxide' named entity 'TSA' named entity 'medRxiv' named entity 'vapor pressure' named entity 'hydrogen peroxide' named entity 'ANSI' named entity 'medRxiv' named entity 'nitrogen' named entity 'COVID-19 pandemic' named entity 'CC-BY-NC-ND 4.0' named entity 'sterilization' named entity 'hydrogen peroxide' named entity 'isolation valve' named entity 'H2O2' named entity 'viruses' named entity 'Raoult's law' named entity 'VHP' named entity 'preprint' named entity '6, 7, 8' named entity 'vacuum gauge' named entity 'sterilization' named entity 'supply chains' named entity 'preprint' named entity 'VHP' named entity 'prevent the spread' named entity 'sterilization' named entity 'Becton Dickinson'

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