About: Hospitalization and Critical Care of 109 Decedents with COVID-19 Pneumonia in Wuhan, China

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About: Hospitalization and Critical Care of 109 Decedents with COVID-19 Pneumonia in Wuhan, China Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Hospitalization and Critical Care of 109 Decedents with COVID-19 Pneumonia in Wuhan, China
Source	Medline; PMC
abstract	Rationale: The current outbreak of coronavirus disease (COVID-19) pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan, China, spreads across national and international borders. The overall death rate of COVID-19 pneumonia in the Chinese population was 4%. Objectives: To describe the process of hospitalization and critical care of patients who died of COVID-19 pneumonia. Methods: This was a multicenter observational study of 109 decedents with COVID-19 pneumonia from three hospitals in Wuhan. Demographic, clinical, laboratory, and treatment data were collected and analyzed, and the final date of follow-up was February 24, 2020. Results: The mean age of 109 decedents with COVID-19 pneumonia was 70.7 years, 35 patients (32.1%) were female, and 85 patients (78.0%) suffered from one or more underlying comorbidities. Multiple organ failure, especially respiratory failure and heart failure, appeared in all patients even at the early stage of disease. Overall, the mean time from onset of symptoms to death was 22.3 days. All 109 hospitalized patients needed admission to an intensive care unit (ICU); however, because of limited availability, only 51 (46.8%) could be admitted. The period from hospitalization to death in the ICU group and non-ICU group was 15.9 days (standard deviation = 8.8 d) and 12.5 days (8.6 d, P = 0.044), respectively. Conclusions: Mortality due to COVID-19 pneumonia was concentrated in patients above the age of 65 years, especially those with major comorbidities. Patients who were admitted to the ICU lived longer than those who were not. Our findings should aid in the recognition and clinical management of such infections, especially with regard to ICU resource allocation.
has issue date	2020-07-01(xsd:dateTime)
bibo:doi	10.1513/annalsats.202003-225oc
bibo:pmid	32255382
has license	cc-by-nc-nd
sha1sum (hex)	5d8e28ed4902e8ced4cffa271a0ce4ed3ce896f3
schema:url	https://doi.org/10.1513/annalsats.202003-225oc
resource representing a document's title	Hospitalization and Critical Care of 109 Decedents with COVID-19 Pneumonia in Wuhan, China
has PubMed Central identifier	PMC7328178
has PubMed identifier	32255382
schema:publication	Ann Am Thorac Soc
resource representing a document's body	covid:5d8e28ed4902e8ced4cffa271a0ce4ed3ce896f3#body_text
is schema:about of	named entity 'FORM' named entity 'ABOUT' named entity 'READERS' named entity 'manuscript' named entity 'ICMJE' named entity 'COMPLETED' named entity 'SUBMITTED' named entity 'TO PROVIDE' named entity 'APPROPRIATE' named entity 'COMPLETENESS' named entity 'PROGRAMMING' named entity 'MANUSCRIPT' named entity 'ACCURACY' named entity 'CONTAINS' named entity 'INTERESTS' named entity 'HOW' named entity 'WORK' named entity 'PURPOSE' named entity 'UNDERSTAND' named entity 'INFORMATION' named entity 'DISCLOSURE' named entity 'data display' named entity 'SUBMIT' named entity 'CONFLICTS' named entity 'DATA DISPLAY' named entity 'STORED' named entity 'SEPARATE' named entity 'PARTS' named entity 'RESPONSIBLE' named entity 'INFLUENCE' named entity 'ALLOWS' named entity 'AUTHOR' named entity 'RECEIVE' named entity 'POTENTIAL' named entity 'OF INTEREST' named entity 'FORM'
is part of of	Hospitalization and Critical Care of 109 Decedents with COVID-19 Pneumonia in Wuhan, China Rationale: The current outbreak of coronavirus disease (COVID-19) pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan, China, spreads across national and international borders. The overall death rate of COVID-19 pneumonia in the Chinese population was 4%. Objectives: To describe the process of hospitalization and critical care of patients who died of COVID-19 pneumonia. Methods: This was a multicenter observational study of 109 decedents with COVID-19 pneumonia from three hospitals in Wuhan. Demographic, clinical, laboratory, and treatment data were collected and analyzed, and the final date of follow-up was February 24, 2020. Results: The mean age of 109 decedents with COVID-19 pneumonia was 70.7 years, 35 patients (32.1%) were female, and 85 patients (78.0%) suffered from one or more underlying comorbidities. Multiple organ failure, especially respiratory failure and heart failure, appeared in all patients even at the early stage of disease. Overall, the mean time from onset of symptoms to death was 22.3 days. All 109 hospitalized patients needed admission to an intensive care unit (ICU); however, because of limited availability, only 51 (46.8%) could be admitted. The period from hospitalization to death in the ICU group and non-ICU group was 15.9 days (standard deviation = 8.8 d) and 12.5 days (8.6 d, P = 0.044), respectively. Conclusions: Mortality due to COVID-19 pneumonia was concentrated in patients above the age of 65 years, especially those with major comorbidities. Patients who were admitted to the ICU lived longer than those who were not. Our findings should aid in the recognition and clinical management of such infections, especially with regard to ICU resource allocation. covid:5d8e28ed4902e8ced4cffa271a0ce4ed3ce896f3#body_text

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