About: Do nutrients and other bioactive molecules from foods have anything to say in the treatment against COVID-19?

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About: Do nutrients and other bioactive molecules from foods have anything to say in the treatment against COVID-19? Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Do nutrients and other bioactive molecules from foods have anything to say in the treatment against COVID-19?
Creator	Battino, Maurizio Quiles, José Battino, J Llopis, Juan Rivas, Lorenzo Rivas-García, J Rivas-García, Lorenzo Sánchez-González, Cristina Sánchez-González, M Varela-López, Alfonso Varela-López, L
Source	Elsevier; Medline; PMC
abstract	The repositioning of therapeutic agents already approved by the regulatory agencies for the use of drugs is very interesting due to the immediacy of their use; similarly, the possibility of using molecules derived from foods, whether nutrients or not, is of great importance, also because of their immediate therapeutic applicability. Candidates for these natural therapies against COVID-19 should show certain effects, such as restoring mitochondrial function and cellular redox balance. This would allow reducing the susceptibility of risk groups and the cascade of events after SARS-CoV-2 infection, responsible for the clinical picture, triggered by the imbalance towards oxidation, inflammation, and cytokine storm. Possible strategies to follow through the use of substances of food origin would include: a) the promotion of mitophagy to remove dysfunctional mitochondria originating from free radicals, proton imbalance and virus evasion of the immune system; b) the administration of transition metals whose redox activity would lead to their own oxidation and the consequent generation of a reduced environment, which would normalize the oxidative state and the intracellular pH; c) the administration of molecules with demonstrated antioxidant capacity; d) the administration of compounds with anti-inflammatory and vasodilatory activity; e) the administration of immunomodulatory compounds.
has issue date	2020-08-22(xsd:dateTime)
bibo:doi	10.1016/j.envres.2020.110053
bibo:pmid	32835682
has license	no-cc
sha1sum (hex)	5cea3904fe6d277ce8db57b2f62be4c981609a81
schema:url	https://doi.org/10.1016/j.envres.2020.110053
resource representing a document's title	Do nutrients and other bioactive molecules from foods have anything to say in the treatment against COVID-19?
has PubMed Central identifier	PMC7442575
has PubMed identifier	32835682
schema:publication	Environ Res
resource representing a document's body	covid:5cea3904fe6d277ce8db57b2f62be4c981609a81#body_text
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