About: Proteomics and disease: opportunities and challenges

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Proteomics and disease: opportunities and challenges
source	Medline; PMC
abstract	Since the human genome was sequenced, there has been intense activity to understand the function of the 30 000 identified genes; attention has now turned to the products of genes — proteins. Proteomics is the large‐scale study of the structure and function of proteins; it includes the rapidly evolving field of disease proteomics, which aims to identify proteins involved in human disease and to understand how their expression, structure and function cause illness. Proteomics has identified proteins that offer promise as diagnostic or prognostic markers, or as therapeutic targets in a range of illnesses, including cancer, immune rejection after transplantation, and infectious diseases such as tuberculosis and malaria; it has the potential to allow patient‐tailored therapy. Some major challenges remain, both technical (eg, detecting “low‐abundance” proteins, and maintaining sample stability) and in data management (eg, correlating changes in proteins with disease processes).
has issue date	2005-06-06(xsd:dateTime)
bibo:doi	10.5694/j.1326-5377.2005.tb06817.x
bibo:pmid	15938685
has license	no-cc
sha1sum (hex)	5c546859a0eca4df7cf465d02dce623f71cd5508
schema:url	https://doi.org/10.5694/j.1326-5377.2005.tb06817.x
resource representing a document's title	Proteomics and disease: opportunities and challenges
has PubMed Central identifier	PMC7168462
has PubMed identifier	15938685
schema:publication	Med J Aust
resource representing a document's body	covid:5c546859a0eca4df7cf465d02dce623f71cd5508#body_text
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