About: Heart rupture repair during huge mediastinal mass resection

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About: Heart rupture repair during huge mediastinal mass resection – case report Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Heart rupture repair during huge mediastinal mass resection – case report
Creator	Abou Chaar, Mohamad Al-Hussaini, Maysa Al-Qudah, Obada Gharaibeh, Azza Jail, Riad Zahra, Khalil
Source	PMC
abstract	BACKGROUND: Ventricular rupture is rarely described in the literature outside the context of myocardial infarction, infection or neoplasm. It is associated with a high mortality rate due to late presentation and delayed surgical intervention, which involves sutureless or sutured techniques. Comprehensive literature review failed to identify any case of intra-operative right ventricular heart rupture followed by myocardial repair and a complete recovery after a prolonged intensive care unit (ICU) stay. CASE PRESENTATION: A 57-year-old previously healthy gentleman presented complaining of a new onset shortness of breath for 2 months. A large mediastinal mass was found on chest imaging and biopsy revealed a thymoma. Patient received a neoadjuvant Cisplatin/Doxorubicin/Cyclophosphamide (CAP) regimen chemotherapy then sternotomy and thymectomy en bloc with anterior pericardium. Post-thymectomy, the patient continued to be hypotensive in recovery despite aggressive fluid resuscitation. He was sent back to theatre, aggressive fluid resuscitation continued, surgical site exploration was done by reopening the sternum, and the bleeding source was identified and controlled, but intraoperative asystole developed. During internal cardiac massage, the right ventricle ruptured with a 3 cm defect which was successfully repaired using a pericardial patch without a bypass machine due to unavailability at our cancer center. The patient remained dependent on mechanical ventilation through tracheostomy for a total of 2 months due to bilateral phrenic nerve paralysis, was discharged from ICU to the surgical floor 66 days after the operation and weaned off ventilator support after 85 days, adequate respiratory and physical rehabilitation followed. Patient is doing very well now with excellent performance, and free of tumor recurrence 30 months after surgery. CONCLUSION: Right ventricular rupture is rarely described outside the context of myocardial infarction and valvular heart disease. Tumor proximity to the heart and neoadjuvant cardiotoxic chemotherapy are the proposed causes for precipitating the cardiac rupture in our case. Post-surgical patients who receive early physical rehabilitation and respiratory physiotherapy have improved survival and outcome.
has issue date	2020-07-06(xsd:dateTime)
bibo:doi	10.1186/s13019-020-01209-9
has license	cc-by
sha1sum (hex)	59ba69cd3eab5ce3444c0de5d77c93c6663d0c79
schema:url	https://doi.org/10.1186/s13019-020-01209-9
resource representing a document's title	Heart rupture repair during huge mediastinal mass resection – case report
has PubMed Central identifier	PMC7336429
schema:publication	J Cardiothorac Surg
resource representing a document's body	covid:59ba69cd3eab5ce3444c0de5d77c93c6663d0c79#body_text
is schema:about of	named entity 'SURGICAL INTERVENTION' named entity 'HEALTHY' named entity 'STERNUM' named entity 'DELAYED' named entity 'EN BLOC' named entity 'PRECIPITATING' named entity 'CONTEXT' named entity 'POST' named entity 'RUPTURED' named entity 'INTRAOPERATIVE' named entity 'COMPLAINING' named entity 'SOURCE' named entity 'MYOCARDIAL INFARCTION' named entity 'TUMOR' named entity 'BLEEDING' named entity 'TRACHEOSTOMY' named entity 'FOLLOWED' named entity 'THYMOMA' named entity 'HEART' named entity 'LATE' named entity 'DISCHARGED' named entity 'LITERATURE' named entity 'SURGICAL SITE' named entity 'DOING' named entity 'LITERATURE REVIEW' named entity 'REGIMEN' named entity 'FAILED' named entity 'PHYSICAL REHABILITATION' named entity 'IMPROVED' named entity 'ICU' named entity 'PERFORMANCE' named entity 'CARDIAC RUPTURE' named entity 'VENTILATOR' named entity 'RECEIVE' named entity 'SURVIVAL' named entity 'MACHINE' named entity 'BILATERAL' named entity 'LARGE' named entity 'ICU' named entity 'Doxorubicin' named entity 'myocardial infarction' named entity 'tumor' named entity 'ICU' named entity 'cancer center' named entity 'internal cardiac massage' named entity 'surgical site' named entity 'ventilator support' named entity 'mechanical ventilation' named entity 'thymectomy' named entity 'mediastinal mass' named entity 'hypotensive' named entity 'asystole' named entity 'shortness of breath' named entity 'Cisplatin' named entity 'physical rehabilitation' named entity 'Cyclophosphamide' named entity 'acute myocardial infarction' named entity 'fluoroscopy' named entity 'post-operative' named entity 'SVC' named entity 'William Harvey' named entity 'SVC' named entity 'cardiac rupture' named entity 'ICU' named entity 'aortic arch' named entity 'mediastinal tumor' named entity 'left ventricular ejection fraction' named entity 'soft tissue' named entity 'Doxorubicin' named entity 'Amiodarone' named entity 'Teflon' named entity 'sutured' named entity 'Cardiac surgical' named entity 'thyroid gland' named entity 'shortness of breath' named entity 'ventricular tachycardia' named entity 'anterior wall' named entity 'blood loss'

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