About: Diagnostic accuracy of two point‐of‐care kits for the diagnosis of Giardia species infection in dogs

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About: Diagnostic accuracy of two point‐of‐care kits for the diagnosis of Giardia species infection in dogs Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Diagnostic accuracy of two point‐of‐care kits for the diagnosis of Giardia species infection in dogs
Creator	Clarke, C Costa, M Mitchell, S Papasouliotis, K
Source	Medline; PMC
abstract	OBJECTIVES: The objective of this study was to compare results obtained by ZnSO(4) Flotation and SNAP (®)Giardia to those generated by the new point‐of‐care tests Single and Triple Rapid. METHODS: Prospective study evaluating 51 canine faecal samples submitted at a reference laboratory for the presence of Giardia spp. Kappa statistics, specificity, sensitivity, positive predictive value (PPV) and negative predictive value (NPV) were calculated by comparing the new tests to the combined results of ZnSO(4) and SNAP tests. RESULTS: There was fair (Single Rapid, j=0·434) to good (Triple Rapid, j =0·797) agreement with the reference tests. At this study's prevalence (59 to 61%), specificities and PPV were high (1·00) with both Rapid tests, but sensitivities and NPV were lower for the Single than for the Triple (0·48 vs 0·83 and 0·55 vs 0·80) tests. At lower prevalence rates, both tests exhibited a high PPV (1·00), but the NPV were higher with the Triple (0·96 to 0·99) than the Single (0·88 to 0·96) Rapid test. CLINICAL SIGNIFICANCE: Both tests exhibited excellent PPV values at all prevalence rates but an excellent NPV only at low prevalence. As the prevalence is likely to be low (<15%) in clinical settings, we propose that these tests may be helpful in the in‐house diagnosis of Giardia spp infection. However, they exhibit lower sensitivity than the combined sensitivity of ZnSO(4) and SNAP tests, particularly in high prevalence settings.
has issue date	2016-06-01(xsd:dateTime)
bibo:doi	10.1111/jsap.12475
bibo:pmid	27251310
has license	no-cc
sha1sum (hex)	5838897ed07a51ee4cbc570b815d11652c5fa47d
schema:url	https://doi.org/10.1111/jsap.12475
resource representing a document's title	Diagnostic accuracy of two point‐of‐care kits for the diagnosis of Giardia species infection in dogs
has PubMed Central identifier	PMC7166413
has PubMed identifier	27251310
schema:publication	J Small Anim Pract
resource representing a document's body	covid:5838897ed07a51ee4cbc570b815d11652c5fa47d#body_text
is schema:about of	named entity 'Corresponding' named entity 'Giardia' named entity 'care' named entity 'NEW' named entity 'PROSPECTIVE STUDY' named entity 'OBTAINED BY' named entity 'EMAIL' named entity 'tests' named entity 'false negative' named entity 'prevalence rate' named entity 'infection' named entity 'predictive' named entity 'PPV' named entity 'species' named entity 'Giardia spp' named entity 'species' named entity 'Giardia' named entity 'prior probability' named entity 'contingency table' named entity 'Sensitivity, specificity' named entity 'Giardia spp' named entity 'cyst' named entity 'physical examination' named entity 'mesh sieve' named entity 'spp' named entity 'parasitological' named entity 'Rapid tests' named entity 'Triple test' named entity 'positive meniscus' named entity 'faecal samples' named entity 'gold standard' named entity 'inoculating loop' named entity 'animal species' named entity 'clinical signs' named entity 'false negatives' named entity 'Giardia' named entity 'faecal samples' named entity 'gold standard' named entity 'Giardia spp' named entity 'faeces' named entity 'confidence intervals' named entity 'zinc sulphate' named entity 'blindness' named entity 'gold standard' named entity 'true positive' named entity 'including dogs' named entity 'microbiology' named entity 'prior probability' named entity 'Faecal' named entity 'clinical disease' named entity 'statistical analysis' named entity 'pipette' named entity 'direct immunofluorescence' named entity 'polymerase chain reaction' named entity 'Giardia spp' named entity 'infection' named entity 'Faecal' named entity 'faecal samples' named entity 'neutered' named entity 'Giardia' named entity 'infection' named entity 'Giardia spp' named entity 'PCR' named entity 'true positive' named entity 'clinical studies' named entity 'true negative' named entity 'Giardia spp' named entity 'cysts' named entity 'knowledge of results' named entity 'Giardia spp' named entity 'clinical evaluation' named entity 'Rapid tests' named entity 'male dogs' named entity 'distilled water' named entity 'diluent' named entity 'direct immunofluorescence' named entity 'infection' named entity 'microscopy'

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