About: Long-term positive severe acute respiratory syndrome coronavirus 2 ribonucleic acid and therapeutic effect of antivirals in patients with coronavirus disease: Case reports

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Long-term positive severe acute respiratory syndrome coronavirus 2 ribonucleic acid and therapeutic effect of antivirals in patients with coronavirus disease: Case reports
Creator	Wei, Bo Wang, Jianrong Wu, Jinzi Cao, Xinghao Hang, Xiaofeng Wang, Junxue Xie, Ying Zhang, Yuanjing
Source	Medline; PMC
abstract	Coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been declared a pandemic. We herein report four COVID-19 cases with long-term positive viral ribonucleic acid (RNA) for about 61 days. Despite treatment with recombinant human interferon, convalescent plasma from COVID-19 patients, arbidol, etc., nucleic acid results were still positive for SARS-CoV-2. After treatment with ritonavir-boosted danoprevir (DNVr, 100/100 mg, once daily), all four patients showed two to three consecutive negative SARS-CoV-2 RNA and were thus discharged from hospital. Therefore, DNVr may be a potentially effective antiviral for COVID-19 patients with long-term positive SARS-CoV-2 RNA.
has issue date	2020-07-20(xsd:dateTime)
bibo:doi	10.1590/0037-8682-0372-2020
bibo:pmid	32696811
has license	cc-by
sha1sum (hex)	560681967888ccef86ea00383ded88150159e35f
schema:url	https://doi.org/10.1590/0037-8682-0372-2020
resource representing a document's title	Long-term positive severe acute respiratory syndrome coronavirus 2 ribonucleic acid and therapeutic effect of antivirals in patients with coronavirus disease: Case reports
has PubMed Central identifier	PMC7375796
has PubMed identifier	32696811
schema:publication	Revista da Sociedade Brasileira de Medicina Tropical
resource representing a document's body	covid:560681967888ccef86ea00383ded88150159e35f#body_text
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