About: Ventilation/perfusion SPECT/CT findings in different lung lesions associated with COVID-19: a case series

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About: Ventilation/perfusion SPECT/CT findings in different lung lesions associated with COVID-19: a case series Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Ventilation/perfusion SPECT/CT findings in different lung lesions associated with COVID-19: a case series
Creator	Bonardel, Gérald Cobes, Nina Grellier, Jean-François Guernou, Mohamed Lussato, David Queneau, Mathieu Songy, Bernard
Source	Medline; PMC
abstract	PURPOSE: The aim of this series of cases is to show the aspects of ventilation/perfusion single-photon emission computed tomography combined with computed tomography (V/Q SPECT/CT) in patients hospitalized for COVID-19 pneumonia, with the worsening of respiratory symptoms raising the suspicion of a pulmonary embolism. Patients did not benefit from CT angiography for various reasons: a contraindication, unavailability of the CT angiography, or a low clinical probability for pulmonary embolism. METHODS: We retrospectively describe the results of the V/Q SPECT/CT of five patients hospitalized for COVID-19 pneumonia in the nuclear medicine departments of the Centre Cardiologique du Nord and of the Delafontaine hospital in Saint-Denis (Ile-de-France, France) between April 2, 2020, and April 10, 2020. These patients had persistent dyspnea or chest pain suggesting pulmonary embolism. RESULTS: The V/Q SPECT/CT allowed to diagnose a pulmonary embolism in one of these five patients. We also noted several characteristics of the perfusion and ventilation depending on the lung lesions on the CT scan. The areas affected by COVID-19 were most often responsible for ventilatory anomalies with a relatively preserved perfusion. In more advanced cases of pneumonia, with alveolar fillings, the perfusion was also reduced or absent in accordance with large ventilation defects. In addition, the healthy parenchyma appeared to benefit from an uptake in ventilation and perfusion. CONCLUSION: V/Q SPECT/CT can play a role in the management of patients hospitalized for COVID-19 for the diagnosis of embolic complications with meticulous hygienic precautions. The different characteristics of the ventilatory and perfusion anomalies related to COVID-19 pneumonia will be confirmed with the next cases. In addition, in this pandemic context and facing a significant infectious risk, the utility of ventilation will also have to be specified.
has issue date	2020-06-18(xsd:dateTime)
bibo:doi	10.1007/s00259-020-04920-w
bibo:pmid	32556400
has license	no-cc
sha1sum (hex)	555c46ad521d4892547a69fc8ffd56dbb17076be
schema:url	https://doi.org/10.1007/s00259-020-04920-w
resource representing a document's title	Ventilation/perfusion SPECT/CT findings in different lung lesions associated with COVID-19: a case series
has PubMed Central identifier	PMC7302725
has PubMed identifier	32556400
schema:publication	Eur J Nucl Med Mol Imaging
resource representing a document's body	covid:555c46ad521d4892547a69fc8ffd56dbb17076be#body_text
is schema:about of	named entity 'COVID-19' named entity 'hygienic' named entity 'embolism' named entity 'utility' named entity 'ventilation' named entity 'embolic' named entity 'COVID-19' named entity 'Nord' named entity 'These' named entity 'aim' named entity 'ventilation' named entity 'describe' named entity 'parenchyma' named entity 'ventilation' named entity 'Ventilation' named entity 'RISK' named entity 'ONE OF' named entity 'RESULTS' named entity 'CT ANGIOGRAPHY' named entity 'SPECT/CT' named entity 'suspicion' named entity 'hospitalized' named entity 'V/Q' named entity 'SPECT/CT' named entity 'Laboratory test' named entity 'perfusion' named entity 'CT scan' named entity 'V/Q' named entity 'April 10' named entity 'patients' named entity 'SPECT/CT' named entity 'areas' named entity 'pneumonia' named entity 'context' named entity 'raising' named entity 'CT angiography' named entity 'SPECT/CT' named entity 'COVID-19' named entity 'perfusion' named entity 'V/Q' named entity 'perfusion' named entity 'alveolar' named entity 'embolic' named entity 'COVID-19' named entity 'parenchyma' named entity 'pneumonia' named entity 'COVID-19' named entity 'perfusion' named entity 'pulmonary embolism' named entity 'V/Q' named entity 'dyspnea' named entity 'pneumonia' named entity 'V/Q' named entity 'case series' named entity 'Ventilation/perfusion' named entity 'COVID-19' named entity 'WHO' named entity '99.9%' named entity 'D-dimers' named entity 'pulmonary embolism' named entity 'France' named entity 'disinfection' named entity 'nuclear medicine' named entity 'dyspnea' named entity 'SPECT/CT' named entity 'perfusion' named entity 'COVID' named entity 'V/Q' named entity 'Informed consent' named entity 'parenchyma' named entity 'Saint-Denis' named entity 'V/Q' named entity 'dyspnea' named entity 'disposable filter' named entity 'capillary'

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