About: Dipeptidyl Peptidase-4: A Potential Therapeutic Target in Diabetic Kidney Disease with SARS-CoV-2 Infection

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Dipeptidyl Peptidase-4: A Potential Therapeutic Target in Diabetic Kidney Disease with SARS-CoV-2 Infection Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Dipeptidyl Peptidase-4: A Potential Therapeutic Target in Diabetic Kidney Disease with SARS-CoV-2 Infection
Creator	Charan Danta, Chhanda
Source	PMC
abstract	[Image: see text] Dipeptidyl peptidase-4 (DPP-4) is expressed ubiquitously in many tissues, including kidney, respiratory tract, and immune cells. Human DPP-4 has been identified as a functional receptor for the spike glycoprotein of the Middle East respiratory syndrome coronavirus. A large interface has been predicted in the docking of DPP-4/SARS-CoV-2 spike protein. Globally, 40% of diabetic patients develop diabetic kidney disease (DKD), a leading cause of end-stage renal disease. DPP-4 inhibitors possess anti-inflammatory properties which suggest their potential implication in DKD and SARS-CoV-2 immunopathogenesis.
has issue date	2020-08-18(xsd:dateTime)
bibo:doi	10.1021/acsptsci.0c00097
has license	no-cc
sha1sum (hex)	534332d477e67ec4e0a462c417b3a0db8cd19157
schema:url	https://doi.org/10.1021/acsptsci.0c00097
resource representing a document's title	Dipeptidyl Peptidase-4: A Potential Therapeutic Target in Diabetic Kidney Disease with SARS-CoV-2 Infection
has PubMed Central identifier	PMC7447076
schema:publication	ACS Pharmacol Transl Sci
resource representing a document's body	covid:534332d477e67ec4e0a462c417b3a0db8cd19157#body_text
is schema:about of	named entity 'Kidney' named entity 'inflammation' named entity 'DKD' named entity 'GLP-1' named entity 'DPP-4 inhibitors' named entity 'glycemia' named entity 'MERS-CoV' named entity 'Wuhan' named entity 'DPP-4 inhibitors' named entity 'SARS-CoV-2' named entity 'renal dysfunction' named entity 'catalase' named entity 'SARS-CoV-2' named entity 'type 2 diabetes' named entity 'sitagliptin' named entity 'infection' named entity 'antibodies' named entity 'SARS-CoV' named entity 'kidney fibrosis' named entity 'DPP-4' named entity 'anti-inflammatory' named entity 'insulin secretion' named entity 'vascular endothelium' named entity 'Saudi Arabia' named entity 'GLP-1' named entity 'adipose tissue' named entity 'inflammation' named entity 'mRNA' named entity 'SARS-CoV-2' named entity 'SARS-CoV-2' named entity 'renal failure' named entity 'Type 2 diabetes' named entity 'type 2 diabetes' named entity 'insulin resistance' named entity 'proximal tubule' named entity 'COVID-19 global pandemic' named entity 'CD26' named entity 'immunopathogenesis' named entity 'human coronavirus' named entity 'insulin secretion' named entity 'Peptidase' named entity 'Infection' named entity 'Dipeptidyl Peptidase-4' named entity 'Diabetic Kidney Disease' named entity 'DPP-4' named entity 'type 2 diabetes' named entity 'NF-κB pathway' named entity 'DPP-4 inhibition' named entity 'receptor' named entity 'Middle East respiratory syndrome' named entity 'glomeruli' named entity 'coronavirus' named entity 'hormone' named entity 'DKD' named entity 'prognosis' named entity 'alogliptin' named entity 'blood pressure' named entity 'metabolism' named entity 'albuminuria' named entity 'DKD' named entity 'global pandemic' named entity 'COVID' named entity 'viral replication' named entity 'mice models' named entity 'angiotensin II' named entity 'Huh-7' named entity 'DPP-4 inhibitor' named entity 'linagliptin' named entity 'SARS-CoV-2' named entity 'SARS-CoV-2' named entity 'comorbidities' named entity 'albuminuria' named entity 'DKD' named entity 'COVID-19 pandemic' named entity 'diabetic' named entity 'GLP-1' named entity 'lymphocytes' named entity 'kidney' named entity 'diabetic kidney disease' named entity 'CD26' named entity 'Italy' named entity 'long-term' named entity 'cytokine storm'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software