About: Genome editing for the treatment of tumorigenic viral infections and virus-related carcinomas

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About: Genome editing for the treatment of tumorigenic viral infections and virus-related carcinomas Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Genome editing for the treatment of tumorigenic viral infections and virus-related carcinomas
Creator	Wang, Hui Yu, Lan Ma, Ding Wu, Ping Li, Xiaomin Gao, Chun Wang, Liming Hu, Zheng Feng, Bei Tian, Xun
Source	Medline; PMC
abstract	Viral infections cause at least 10%–15% of all human carcinomas. Over the last century, the elucidation of viral oncogenic roles in many cancer types has provided fundamental knowledge on carcinogenetic mechanisms and established a basis for the early intervention of virus-related cancers. Meanwhile, rapidly evolving genome-editing techniques targeting viral DNA/RNA have emerged as novel therapeutic strategies for treating virus-related carcinogenesis and have begun showing promising results. This review discusses the recent advances of genome-editing tools for treating tumorigenic viruses and their corresponding cancers, the challenges that must be overcome before clinically applying such genome-editing technologies, and more importantly, the potential solutions to these challenges.
has issue date	2018-04-12(xsd:dateTime)
bibo:doi	10.1007/s11684-017-0572-1
bibo:pmid	29651774
has license	no-cc
sha1sum (hex)	52f7602418e1ec65877ccf6b9dfb6504d455ce6a
schema:url	https://doi.org/10.1007/s11684-017-0572-1
resource representing a document's title	Genome editing for the treatment of tumorigenic viral infections and virus-related carcinomas
has PubMed Central identifier	PMC7088620
has PubMed identifier	29651774
schema:publication	Front Med
resource representing a document's body	covid:52f7602418e1ec65877ccf6b9dfb6504d455ce6a#body_text
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