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About:
Combating the Coronavirus Pandemic: Early Detection, Medical Treatment, and a Concerted Effort by the Global Community
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An Entity of Type :
schema:ScholarlyArticle
, within Data Space :
covidontheweb.inria.fr
associated with source
document(s)
Type:
Academic Article
research paper
schema:ScholarlyArticle
New Facet based on Instances of this Class
Attributes
Values
type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
has title
Combating the Coronavirus Pandemic: Early Detection, Medical Treatment, and a Concerted Effort by the Global Community
Creator
Huang, Wei
Li, Xiaosong
Liu, Kai
Chan,
Goh, Yi
Liu, Xiaogang
Luo, Zichao
Tao, Jun
Yan, Shuangqian
Yi, Zhigao
Zhang, Hongjie
Ang, Yan
Jin, Melgious
Siew, Yin
Source
Medline; PMC
abstract
The World Health Organization (WHO) has declared the outbreak of 2019 novel coronavirus, known as 2019-nCoV, a pandemic, as the coronavirus has now infected over 2.6 million people globally and caused more than 185,000 fatalities as of April 23, 2020. Coronavirus disease 2019 (COVID-19) causes a respiratory illness with symptoms such as dry cough, fever, sudden loss of smell, and, in more severe cases, difficulty breathing. To date, there is no specific vaccine or treatment proven effective against this viral disease. Early and accurate diagnosis of COVID-19 is thus critical to curbing its spread and improving health outcomes. Reverse transcription-polymerase chain reaction (RT-PCR) is commonly used to detect the presence of COVID-19. Other techniques, such as recombinase polymerase amplification (RPA), loop-mediated isothermal amplification (LAMP), clustered regularly interspaced short palindromic repeats (CRISPR), and microfluidics, have allowed better disease diagnosis. Here, as part of the effort to expand screening capacity, we review advances and challenges in the rapid detection of COVID-19 by targeting nucleic acids, antigens, or antibodies. We also summarize potential treatments and vaccines against COVID-19 and discuss ongoing clinical trials of interventions to reduce viral progression.
has issue date
2020-06-16
(
xsd:dateTime
)
bibo:doi
10.34133/2020/6925296
bibo:pmid
32607499
has license
cc-by
sha1sum (hex)
52ceadff361c2abd1065c4372719976a33f08922
schema:url
https://doi.org/10.34133/2020/6925296
resource representing a document's title
Combating the Coronavirus Pandemic: Early Detection, Medical Treatment, and a Concerted Effort by the Global Community
has PubMed Central identifier
PMC7315394
has PubMed identifier
32607499
schema:publication
Research (Wash D C)
resource representing a document's body
covid:52ceadff361c2abd1065c4372719976a33f08922#body_text
is
schema:about
of
named entity 'Detection'
named entity 'Coronavirus'
named entity 'COVID-19'
named entity 'Ribavirin'
named entity '2019-nCoV'
named entity 'cytoplasm'
named entity 'lung failure'
named entity 'proteases'
named entity 'proteases'
named entity 'COVID'
named entity 'virus'
named entity 'RNA'
named entity 'pancreas'
named entity 'HIV'
named entity 'RNA'
named entity '2019-nCoV'
named entity 'People's Republic of China'
named entity 'RTP'
named entity 'blood coagulation'
named entity 'Wuhan'
named entity 'zinc'
named entity 'CRISPR'
named entity 'immunoassays'
named entity 'long-term'
named entity 'arbidol'
named entity 'COVID'
named entity 'COVID-19'
named entity 'TCM'
named entity 'live attenuated vaccines'
named entity 'proteases'
named entity 'TCM'
named entity 'COVID-19'
named entity 'adenovirus'
named entity 'acute respiratory distress syndrome'
named entity 'drug discovery'
named entity 'malnourishment'
named entity 'clinical trial'
named entity 'protein'
named entity 'poly-A tail'
named entity 'HTS'
named entity 'MERS'
named entity 'nucleocapsid'
named entity 'pulmonary disorders'
named entity 'chest CT'
named entity 'antibody'
named entity 'RNA'
named entity 'structural proteins'
named entity 'expression vector'
named entity 'protein'
named entity 'oxygen therapy'
named entity '2019-nCoV'
named entity 'TEM'
named entity 'COVID'
named entity 'reactive oxygen species'
named entity 'Chloroquine'
named entity 'SARS-CoV'
named entity 'COVID-19'
named entity 'nucleotides'
named entity 'ivermectin'
named entity 'host cells'
named entity 'China'
named entity '2019-nCoV'
named entity 'noncovalent interactions'
named entity 'quinine'
named entity 'sensitivity, specificity'
named entity 'ACE2'
named entity 'nonstructural proteins'
named entity 'COVID'
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