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About:
The impact of the COVID‐19 outbreak on liver transplantation programs in Northern Italy
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An Entity of Type :
schema:ScholarlyArticle
, within Data Space :
covidontheweb.inria.fr
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document(s)
Type:
Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
title
The impact of the COVID‐19 outbreak on liver transplantation programs in Northern Italy
Creator
Daniel, Yiu
De, |
Marco, Angrisani
Umberto, Maggi
Colledan, |
Consonni, |
Defeo, |
Fornoni Gianluca, |
I E F C O M M U N I C A T I O N, B
Luciano, Carlis
Maria, T
Piccolo, |
Regalia, |
Rossi, |
source
Medline; PMC; WHO
abstract
In January 2020, Novel Coronavirus Disease 2019 (COVID‐19) resulted in a global pandemic, creating uncertainty toward the management of liver transplantation (LT) programs. Lombardy has been the most affected region in Italy: the current mortality rate of COVID‐19 patients is 18.3% (10 022 deaths; April 10th) with hospitals in Lombardy having to expand the total number of ICU beds from 724 to 1381 to accommodate infected patients. There has been a drastic decrease in liver donors. From February 23rd until April 10th, 17 LTs were performed in Lombardy. Mean donor age was 49 years (range 18‐74) whereas mean recipient age was 55 (13‐69); mean MELD score was 12 (6‐24). All donors underwent screening for SARS‐CoV‐2 prior to LT. Two patients tested positive after LT, and one patient died for COVID on POD 30. Sixteen patients are alive after an average of 30 days post‐LT (range 3‐46). 10 patients have been discharged. This study has found no specific reason concerning the safety of recipients, to stop LT programs. Several key lessons from our experience are reported. However, due to the complex circumstances which surround the viral outbreak, the cessation or a reduction in LT activity is a pragmatic requirement.
has issue date
2020-05-22
(
xsd:dateTime
)
bibo:doi
10.1111/ajt.15948
bibo:pmid
32330351
has license
no-cc
sha1sum (hex)
5276e926bceb4a0aa0fe1ad5acced88bef4a9213
schema:url
https://doi.org/10.1111/ajt.15948
resource representing a document's title
The impact of the COVID‐19 outbreak on liver transplantation programs in Northern Italy
has PubMed Central identifier
PMC7264498
has PubMed identifier
32330351
schema:publication
Am J Transplant
resource representing a document's body
covid:5276e926bceb4a0aa0fe1ad5acced88bef4a9213#body_text
is
schema:about
of
named entity 'liver transplantation'
named entity 'liver transplants'
named entity 'Lombardy'
named entity 'Italy'
named entity 'Wuhan'
named entity 'ICU beds'
named entity 'Italy'
named entity 'American Journal of Transplantation'
named entity 'degree of uncertainty'
named entity '95% CI'
named entity 'Lombardy'
named entity 'February 23'
named entity 'coronavirus outbreak'
named entity 'Italy'
named entity 'viral outbreak'
named entity 'liver transplant'
named entity 'liver transplants'
named entity 'BMI'
named entity 'collected data'
named entity 'risk/benefit'
named entity 'infection'
named entity 'Lombardy'
named entity 'liver'
named entity 'COVID-19'
named entity 'ICU beds'
named entity 'liver disease'
named entity 'SARS-CoV-2'
named entity 'liver'
named entity 'liver transplant'
named entity 'COVID-19'
named entity 'ICU'
named entity 'liver transplants'
named entity 'diverse populations'
named entity 'Lombardy'
named entity 'liver disease'
named entity 'univariate'
named entity 'infection'
named entity 'Lombardy'
named entity 'Liver Transplant'
named entity 'COVID-19'
named entity 'Northern Italy'
named entity 'Lombardy'
named entity 'Lombardy'
named entity 'MELD'
named entity 'immunosuppressive'
named entity 'liver transplants'
named entity 'confidence intervals'
named entity 'prognosis'
named entity 'chest CT scan'
named entity 'prognosis'
named entity 'COVID-19'
named entity 'Italy'
named entity 'ischemia'
named entity 'liver transplant'
named entity 'Statistical analysis'
named entity 'Poisson regression'
named entity 'liver'
named entity 'prognosis'
named entity 'Sars-CoV-2'
named entity 'COVID-19'
named entity 'Liver'
named entity 'coronavirus outbreak'
named entity 'Stata'
named entity 'coronavirus outbreak'
named entity 'liver'
named entity 'ICU'
named entity 'liver'
named entity 'immunosuppression'
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