About: Hematology and Oncology in Critical Illness

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Hematology and Oncology in Critical Illness
Creator	Howard, Scott Rajasekaran, Surender Brandão, Leonardo Gow, Kenneth Tamburro, Robert
source	PMC
abstract	This chapter will focus on a variety of hematologic issues pertinent to the care of critically ill children. This is an area of intense research with the pathophysiology underlying these clinical conditions becoming progressively better understood. This improved understanding has resulted in new therapeutic strategies that are being assessed in multicenter clinical trials. The chapter will begin by describing the incidence and pathophysiologic significance of anemia in the pediatric intensive care unit (PICU) providing a differential diagnosis of the many conditions that may present with anemia in this setting. The chapter will next consider disseminated intravascular coagulation (DIC) focusing on the pathophysiology of a condition that has been associated with much morbidity and mortality. The underlying conditions predisposing to DIC will be detailed as well as a number of treatment options that have been implemented in clinical trials. In addition to DIC, thrombocytopenia may be caused by a number of other clinical conditions important to the pediatric critical care provider. The clinical and prognostic significance of thrombocytopenia will be addressed and a focused differential diagnosis will be provided. Thrombotic disorders are becoming increasingly recognized in children and are a particular concern for the pediatric intensivist. The epidemiology of thromboembolism in children will be reviewed focusing on the conditions most commonly associated with these thromboses. Finally, a chapter on hematologic issues in the critically ill child would not be complete without a discussion of sickle cell disease. Acute chest syndrome, one of the most frequent complications of sickle cell disease resulting in the need for intensive care services, will be discussed in detail.
has issue date	2011-12-16(xsd:dateTime)
bibo:doi	10.1007/978-0-85729-923-9_38
has license	no-cc
sha1sum (hex)	5260a71df26d9c28551f04bdf43fabf540beb9ab
schema:url	https://doi.org/10.1007/978-0-85729-923-9_38
resource representing a document's title	Hematology and Oncology in Critical Illness
has PubMed Central identifier	PMC7178863
schema:publication	Pediatric Critical Care Study Guide
resource representing a document's body	covid:5260a71df26d9c28551f04bdf43fabf540beb9ab#body_text
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