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  • Motivation Being able to efficiently call variants from the increasing amount of sequencing data daily produced from multiple viral strains is of the utmost importance, as demonstrated during the COVID-19 pandemic, in order to track the spread of the viral strains across the globe. Results We present MALVIRUS, an easy-to-install and easy-to-use web application that assists users in (1) computing a variant catalog consisting in a set of population SNP loci from the population sequences and (2) efficiently calling variants of the catalog that are in the sample. Tests on Illumina and Nanopore samples prove the efficiency and the effectiveness of MALVIRUS in genotyping a SARS-CoV-2 strain sample with respect to GISAID data. Availability MALVIRUS is freely available at https://algolab.github.io/MALVIRUS/. Contact yuri.pirola@unimib.it Supplementary information Supplementary data are available at bioRxiv online.
Subject
  • Software architecture
  • Scottish National Party
  • 2019 disasters in China
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