About: Middle East respiratory syndrome coronavirus (MERS-CoV) — Surveillance and testing in North England from 2012 to 2019

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Middle East respiratory syndrome coronavirus (MERS-CoV) — Surveillance and testing in North England from 2012 to 2019
Creator	Ahmad, Shazaad Davies, Emma Guiver, Malcolm Hesketh, Louise Machin, Nicholas Turner, Andrew Farooq, Hamzah
source	Elsevier; Medline; PMC
abstract	BACKGROUND: Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in Saudi Arabia in 2012 and caused an epidemic in the Middle East. Public Health England (PHE) Manchester is one of the two PHE centres in the UK that perform testing for MERS-CoV. The results of the PHE Manchester MERS surveillance from 2012 to 2019 are presented in this report. METHODS: Retrospective data were collected for returning travellers from the Middle East fitting the PHE MERS case definition. Respiratory samples were tested for respiratory viruses and MERS-CoV using an in-house RT-PCR assay. RESULTS: Four hundred and twenty-six (426) samples from 264 patients were tested for MERS Co-V and respiratory viruses. No MERS-CoV infections were identified by PCR. Fifty-six percent of samples were PCR positive for viral or bacterial pathogen with Influenza A as the predominant virus (44%). Sixty-two percent of all patients had a pathogen identified with the highest positivity from sputum samples. Patients with multiple samples demonstrated a 100% diagnostic yield. CONCLUSIONS: Although no cases of MERS were identified, the majority of patients had Influenza infection for which oseltamivir treatment was indicated and isolation warranted. Sputum samples were the most useful in diagnosing respiratory viruses with a 100% diagnostic yield from patients with multiple samples.
has issue date	2020-01-28(xsd:dateTime)
bibo:doi	10.1016/j.ijid.2020.01.043
bibo:pmid	32004690
has license	no-cc
sha1sum (hex)	5108ce6531c57ac210900865b5170794544c4692
schema:url	https://doi.org/10.1016/j.ijid.2020.01.043
resource representing a document's title	Middle East respiratory syndrome coronavirus (MERS-CoV) — Surveillance and testing in North England from 2012 to 2019
has PubMed Central identifier	PMC7129156
has PubMed identifier	32004690
schema:publication	Int J Infect Dis
resource representing a document's body	covid:5108ce6531c57ac210900865b5170794544c4692#body_text
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