About: Elimination of Staphylococcus aureus nasal carriage in intensive care patients lowers infection rates

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Elimination of Staphylococcus aureus nasal carriage in intensive care patients lowers infection rates Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Elimination of Staphylococcus aureus nasal carriage in intensive care patients lowers infection rates
Creator	Van Belkum, Alex Danesh, Leila Fooladvand, Saeed Ghaznavi-Rad, Ehsanollah Nejad, Saiedi Sarmadian, Hossein Zeinab, &
source	PMC
abstract	This study surveys the clinical relevance of the nasal Staphylococcus aureus colonization status on intensive care unit (ICU)–acquired S. aureus infections and compares molecular characteristics of isolates from the nose and infectious sites. The 390 patients included comprised 278 non-carriers and 112 carriers. Among the carriers, 56 were decolonized with mupirocin. Decolonization was verified through a second (negative) culture. Spa typing and virulence gene profiling were performed for all isolates. Twenty six S. aureus infections were detected in the carriage group and 20 in the non-carriage group. Eighteen of these 26 (69.2%) infections were among carriers, and 8 of these 26 (30.8%) infections occurred among decolonized carriers (p = 0.02). Overall, 31/112 (27.7%) of the colonized patients and 25/46 (60.1%) of infection were due to methicillin-resistant S. aureus (MRSA). The highest frequency virulence genes were sea and hlg (both 100%) in nasal isolates and sea, hlg, fnb, and clf (100%) for infectious isolates. t030 was the most abundant spa type overall. S. aureus carriers were more likely to develop S. aureus infection compared with decolonized and non-carrying patients. The sources of ICU S. aureus infection appear to be exogenous mostly, and a predominant clone (spa type 030) plays an important role. We confirm that nasal mupirocin treatment prevents ICU infections even when there is an increased prevalence of nosocomial MRSA.
has issue date	2019-11-12(xsd:dateTime)
bibo:doi	10.1007/s10096-019-03729-2
bibo:pmid	31720943
has license	no-cc
sha1sum (hex)	50b5d3fb7d1eeb380336ca3a7b818135ee4931bb
schema:url	https://doi.org/10.1007/s10096-019-03729-2
resource representing a document's title	Elimination of Staphylococcus aureus nasal carriage in intensive care patients lowers infection rates
has PubMed Central identifier	PMC7224068
has PubMed identifier	31720943
schema:publication	Eur J Clin Microbiol Infect Dis
resource representing a document's body	covid:50b5d3fb7d1eeb380336ca3a7b818135ee4931bb#body_text
is schema:about of	named entity 'intensive care unit (ICU)' named entity 'ICU' named entity 'Overall' named entity 'This' named entity 'S. aureus' named entity 'infections' named entity 'carriage' named entity 'Staphylococcus aureus' named entity 'infection' named entity 'The' named entity 'hlg' named entity 'mupirocin' named entity 'carriage' named entity 'Spa' named entity 'typing' named entity 'patients' named entity 'The' named entity 'surveys' named entity 'S. aureus' named entity 'methicillin-resistant S. aureus' named entity 'ICU' named entity 'fnb' named entity 'MRSA' named entity 'S. aureus' named entity 'Staphylococcus aureus' named entity 'infection' named entity 'intensive care' named entity 'genes' named entity 'infections' named entity 'virulence factors' named entity 'ICUs' named entity 'gene' named entity 'bacteremia' named entity 'S. aureus' named entity 'Methicillin-resistant S. aureus' named entity 'adhesive proteins' named entity 'antibiotics' named entity 'exogenous' named entity 'S. aureus' named entity 'infection' named entity 'Arak' named entity 'S. aureus' named entity 'commensal flora' named entity 'pvl' named entity 'pvl' named entity 'ICU' named entity 'Microsoft Office' named entity 'ICU' named entity 'Iran' named entity 'S. aureus' named entity 'TSST' named entity 'PCR' named entity 'Microbiology' named entity 'MRSA' named entity 'Tehran' named entity 'gene' named entity 'S. aureus' named entity 'fnb' named entity 'methicillin' named entity 'MRSA' named entity 'MRSA' named entity 'intensive care units' named entity 'infection' named entity 'endogenous' named entity 'toxic shock syndrome toxin' named entity 'S. aureus' named entity 'gene' named entity 'infection' named entity 'S. aureus' named entity 'mecA' named entity 'S. aureus' named entity 'opportunistic human pathogen' named entity 'hospital settings' named entity 'surgical site infections' named entity 'ICUs'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software