About: Effect of acupuncture on uncoupling protein 1 gene expression for brown adipose tissue of obese rats

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Effect of acupuncture on uncoupling protein 1 gene expression for brown adipose tissue of obese rats
Creator	Feng-Min, Sun Li, Chao-Jun Liu, Zhi-Cheng Miao-Hua (, Zhu Wu, Hai-Tao Xu, Bing-Guo Zhang, Zhong-Cheng Zhao, Dong-Hong
Source	PMC
abstract	Objective; To explore the effects of acupuncture on the expression of uncoupling protein 1 (UCP(1)) gene of brown adipose tissue (BAT) in obese rats.Methods: The expression of UCP(1) gene of BAT was determined with RT-PCR technique. The changes of body weight, Lee’s index, body fat, and the expression of UCP(1) gene of BAT in obese rats were observed before and after acupuncture.Results: The body weight, Lee’s index, body fat in obese rats were all markedly higher than those in normal rats, but the expression of UCP(1) gene of BAT in obese rats was all lower than that in normal rats. There were negative correlation between the obesity index and the expression of UCP(1) gene in BAT. After acupuncture the marked effect of weight loss was achieved while the expression of UCP(1) gene of BAT obviously increased in obese rats.Conclusion: The abnormal reduction for expression of UCP(1) gene of BAT might be an important cause for the obesity. To promote the expression of UCP(1) in obese organism might be an important cellular and molecular mechanism in anti-obesity effect by acupuncture.
has issue date	2003-01-01(xsd:dateTime)
bibo:doi	10.1007/bf02838034
has license	no-cc
sha1sum (hex)	4ffa31d98c32c5955c6d5461b596a974d686026c
schema:url	https://doi.org/10.1007/bf02838034
resource representing a document's title	Effect of acupuncture on uncoupling protein 1 gene expression for brown adipose tissue of obese rats
has PubMed Central identifier	PMC7089448
schema:publication	Chin J Integr Med
resource representing a document's body	covid:4ffa31d98c32c5955c6d5461b596a974d686026c#body_text
is schema:about of	named entity 'gene' named entity 'normal' named entity 'body weight' named entity 'BAT' named entity 'CORRELATION' named entity 'GENE' named entity 'expression' named entity 'higher' named entity 'gene' named entity 'Objective' named entity 'UCP1' named entity 'obese' named entity 'BAT' named entity 'UCP1' named entity 'obesity' named entity 'organism' named entity 'gene' named entity 'uncoupling protein 1' named entity 'UCP1' named entity 'UCP1' named entity 'BAT' named entity 'obese' named entity 'gene' named entity 'acupuncture' named entity 'correlation' named entity 'Uncoupling Protein 1' named entity 'Acupuncture' named entity 'Obese' named entity 'BAT' named entity 'Reverse transcription' named entity 'acupuncture' named entity 'acupuncture' named entity 'UCP1' named entity 'serum' named entity 'insulin' named entity 'white adipose tissue' named entity 'pathogenesis' named entity 'thyroxin' named entity 'salivary amylase' named entity 'gene expression' named entity 'obesity' named entity 'mitochondria' named entity 'oxidized' named entity 'actin' named entity 'UCP1' named entity 'gene expression' named entity 'triglyceride' named entity 'UCPI' named entity 'up-regulate' named entity 'gene expression' named entity 'UCP1' named entity 'plasma' named entity 'INSR' named entity 'metabolism' named entity 'body weight' named entity 'UCP3' named entity 'PCR reaction' named entity 'pathogenesis' named entity 'corn' named entity 'Nanjing Military Region' named entity 'insulin receptor' named entity 'body weight' named entity 'mitochondria' named entity 'obesity' named entity 'obesity' named entity 'BAT' named entity 'PCR reaction' named entity 'gene' named entity 'INSR' named entity 'obese' named entity 'ultraviolet' named entity 'UCP1' named entity 'UCP1' named entity 'Promega' named entity 'hotmail' named entity 'acupuncture'

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