About: Solid‐phase synthesis and screening of a library of C‐terminal arginine peptide aldehydes against Murray Valley encephalitis virus protease

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About: Solid‐phase synthesis and screening of a library of C‐terminal arginine peptide aldehydes against Murray Valley encephalitis virus protease Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Solid‐phase synthesis and screening of a library of C‐terminal arginine peptide aldehydes against Murray Valley encephalitis virus protease
Creator	Hill, Jeffrey Joy, Joma Koppens, Merran
Source	Medline; PMC
abstract	Murray Valley encephalitis virus is a member of the flavivirus group, a large family of single‐stranded RNA viruses, which cause serious disease in all regions of the world. Unfortunately, no suitable antivirals are available, and there are commercial vaccines for only three flaviviruses. The solid‐phase synthesis of a library of 400 C‐terminal arginine peptide aldehydes and their screening against Murray Valley encephalitis virus protease are demonstrated. The library was utilised to elucidate several tripeptide sequences that can be used as inhibitors in further SAR studies. Copyright © 2012 European Peptide Society and John Wiley & Sons, Ltd.
has issue date	2012-09-18(xsd:dateTime)
bibo:doi	10.1002/psc.2450
bibo:pmid	22991186
has license	no-cc
sha1sum (hex)	4f43f6879d1a2da804ec2ecb793218ceb51c79b3
schema:url	https://doi.org/10.1002/psc.2450
resource representing a document's title	Solid‐phase synthesis and screening of a library of C‐terminal arginine peptide aldehydes against Murray Valley encephalitis virus protease
has PubMed Central identifier	PMC7167811
has PubMed identifier	22991186
schema:publication	J Pept Sci
resource representing a document's body	covid:4f43f6879d1a2da804ec2ecb793218ceb51c79b3#body_text
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