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  • Recent years have seen unprecedented investment in research and development for countermeasures for high-threat pathogens, including specific and ambitious objectives for development of diagnostics, therapeutics, and vaccines. The inadequate availability of biological reference materials for these pathogens poses a genuine obstacle in pursuit of these objectives, and the lack of a comprehensive and equitable framework for developing reference materials is a weakness. We outline the need for internationally standardized biological materials for high-threat pathogens as a core element of global health security. We also outline the key components of a framework for addressing this deficiency.
Subject
  • Virology
  • Research
  • Vaccination
  • Vaccines
  • Infectious diseases
  • Innovation
  • Research and development
  • Global health
  • Organic chemistry
  • Product development
  • Organic compounds
  • 18th-century inventions
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