About: Histopathological and immunohistochemical findings in lymphoid tissues of the endangered Iberian lynx (Lynx pardinus)

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About: Histopathological and immunohistochemical findings in lymphoid tissues of the endangered Iberian lynx (Lynx pardinus) Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Histopathological and immunohistochemical findings in lymphoid tissues of the endangered Iberian lynx (Lynx pardinus)
Creator	Peña, Laura Sánchez, Belén Benito, Alberto Garcia, Pilar Alenza, Pérez Dolores, M Ngeles Jiménez, M
Source	Elsevier; PMC
abstract	Abstract The Iberian lynx (Lynx pardinus) is the most threatened wild feline in the world. Little is known about the diseases and pathology that affect this animal. The aim of this study was to evaluate the histopathological status of the peripheral lymphoid tissues and thymus of Iberian lynxes necropsied between 1998 and 2003. Seventeen animals including females (n=8) and males (n=9), age range of 10 months to 16 years, with different causes of death were histopathologically and immunohistochemically (anti-CD3, CD79, MAC387, CD68) studied. Feline immunosuppressive virus laboratorial tests were negative. Five individuals presented neoplasia and/or tuberculosis. All animals presented some degree of both B and T cells depletion in peripheral lymphoid tissues and follicular hyalinosis in the center of depleted follicles. A viral origin of the lymphoid depletion is postulated although other causes (inbreeding, stress, toxic) are not ruled out. The loss of the effectiveness of the immune system increases the vulnerability of the critically endangered Iberian lynx to pathogens.
has issue date	2006-05-31(xsd:dateTime)
bibo:doi	10.1016/j.cimid.2006.01.003
has license	els-covid
sha1sum (hex)	4ef933bccb8f6321b09ead033cdbe7a293d6d671
schema:url	https://doi.org/10.1016/j.cimid.2006.01.003
resource representing a document's title	Histopathological and immunohistochemical findings in lymphoid tissues of the endangered Iberian lynx (Lynx pardinus)
has PubMed Central identifier	PMC7136978
schema:publication	Comparative Immunology, Microbiology and Infectious Diseases
resource representing a document's body	covid:4ef933bccb8f6321b09ead033cdbe7a293d6d671#body_text
is schema:about of	named entity 'est' named entity 'aim' named entity 'wild' named entity 'follicular' named entity 'males' named entity 'mois' named entity 'immunohistochemically' named entity 'immunosuppressive' named entity 'chez' named entity 'Little' covid:arg/4ef933bccb8f6321b09ead033cdbe7a293d6d671 named entity 'viral' named entity 'diseases' named entity 'inbreeding' named entity 'FIV' named entity 'Résumé' named entity 'origin' named entity 'Five' named entity 'dix' named entity 'tissues' named entity 'degree' named entity 'ans' named entity 'CD79' named entity 'evaluate' named entity 'Lynx pardinus' named entity 'virus' named entity 'Iberian lynx' named entity 'CD79' named entity 'd'Espagne' named entity 'histopathologically' named entity 'CD3' named entity 'CD79' named entity 'Iberian lynx' named entity 'Iberian lynxes' named entity 'lymphoid tissues' named entity 'Iberian lynx' named entity 'Lynx pardinus' named entity 'tuberculosis' named entity 'medulla' named entity 'lymph nodes' named entity 'tissue samples' named entity 'lymph nodes' named entity 'anesthesia' named entity 'leukocyte' named entity 'alternative hypothesis' named entity 'critically endangered' named entity 'secondary antibody' named entity 'lynx' named entity 'clone' named entity 'CD3' named entity 'transitional epithelium' named entity 'tumors' named entity 'CD68' named entity 'pressure cooker' named entity 'thymic involution' named entity 'histological' named entity 'tuberculosis' named entity 'serology' named entity 'lymph node' named entity 'Iberian lynxes' named entity 'dead animals' named entity 'spleen' named entity 'immunosuppressive' named entity 'lymphoid follicles' named entity 'European Union' named entity 'tissue samples' named entity 'domestic cats' named entity 'formalin' named entity 'mitogens' named entity 'tuberculosis' named entity 'thymus' named entity 'domestic cat' named entity 'spleen' named entity 'dendritic cells' named entity 'lymphoid organ' named entity 'PCR' named entity 'CD79'

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