About: Herbal Medicine for the Treatment of Coronavirus Disease 2019 (COVID-19): A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Herbal Medicine for the Treatment of Coronavirus Disease 2019 (COVID-19): A Systematic Review and Meta-Analysis of Randomized Controlled Trials Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Herbal Medicine for the Treatment of Coronavirus Disease 2019 (COVID-19): A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Creator	Lee, Hye Ang, Lin Lee, Myeong Song, Eunhye
Source	Medline; PMC
abstract	Background: The coronavirus disease 2019 (COVID-19) pandemic has caused a worldwide outbreak of respiratory illness. This review aims to evaluate the effectiveness and adverse events of herbal medicines for the treatment of COVID-19. Methods: Twelve databases were searched through 12 May 2020. Randomized controlled trials (RCTs) and quasi-RCTs assessing the effects of herbal medicines for the treatment of COVID-19 were eligible. The study selection and data extraction were performed by two independent reviewers. The Cochrane risk of bias tool was used for the assessment of the risk of bias in all included RCTs. Mean differences (MDs), risk ratios (RRs) and odds ratios (ORs) with 95% confidence intervals (CIs) were calculated, and the effect sizes of the studies were pooled. Results: Seven RCTs with a total of 855 patients were included. All included trials compared the combined therapy of herbal medicine with Western medicine to Western medicine alone. The combined therapy significantly improved the total effective rate (RR 1.23, 95% CI 1.13 to 1.34, p < 0.001), cough symptom disappearance rate (RR 1.45, 95% CI 1.12 to 1.89, p = 0.005), and sputum production symptom disappearance rate (RR 1.73, 95% CI 1.19 to 2.50, p = 0.004). Beneficial effects of the combined therapy were also seen in TCM syndrome score of cough (MD −1.18, 95% CI −1.34 to −1.03, p < 0.001), fever (MD −0.62, 95% CI −0.79 to −0.45, p < 0.001), dry and sore throat (MD −0.83, 95% CI −1.45 to −0.20, p = 0.009), and fatigue (MD −0.60, 95% CI −1.04 to −0.17, p = 0.007). The overall risk of bias of the included studies was unclear. No serious adverse events were reported. Conclusion: Significant effects of the combined therapy of herbal medicine with Western medicine were found, and revealed the potential role of herbal medicine in treating COVID-19. More high-quality RCTs are needed to further validate the effectiveness and adverse events of herbal medicine in the treatment of COVID-19.
has issue date	2020-05-23(xsd:dateTime)
bibo:doi	10.3390/jcm9051583
bibo:pmid	32456123
has license	cc-by
sha1sum (hex)	4db4b437ee1ea9a01b9bda41f74b7e3c4c87652c
schema:url	https://doi.org/10.3390/jcm9051583
resource representing a document's title	Herbal Medicine for the Treatment of Coronavirus Disease 2019 (COVID-19): A Systematic Review and Meta-Analysis of Randomized Controlled Trials
has PubMed Central identifier	PMC7290825
has PubMed identifier	32456123
schema:publication	J Clin Med
resource representing a document's body	covid:4db4b437ee1ea9a01b9bda41f74b7e3c4c87652c#body_text
is schema:about of	covid:arg/4db4b437ee1ea9a01b9bda41f74b7e3c4c87652c named entity 'herbal medicine' named entity 'herbal medicine' named entity 'symptom' named entity 'sore throat' named entity 'adverse events' named entity 'adverse events' named entity 'COVID' named entity 'COVID-19' named entity 'TCM' named entity 'assessment of the risk' named entity 'coronavirus disease 2019' named entity '0.45' named entity 'confidence intervals' named entity 'herbal medicines' named entity 'RCTs' named entity 'Meta-Analysis' named entity 'herbal treatment' named entity 'Clinical Trial' named entity 'TCM' named entity 'cohort studies' named entity 'cough' named entity 'significant results' named entity 'Ribavirin' named entity 'antibiotic' named entity 'COVID' named entity 'cough' named entity 'white blood cell' named entity 'herbal medicine' named entity 'control groups' named entity 'Western medicine' named entity 'double-blinded' named entity 'C-reactive protein' named entity 'clinical trials' named entity 'significant effect' named entity 'Western medicine' named entity 'coronavirus disease 2019' named entity 'Herbal medicine' named entity 'allocation concealment' named entity 'sputum production' named entity '11 March 2020' named entity 'fever' named entity 'complete blood count' named entity 'lymphocyte' named entity 'cough' named entity 'Symptom' named entity 'AEs' named entity 'neutrophil' named entity 'Clinical Trials Registry' named entity 'mainland China' named entity 'breastfeeding' named entity 'coronavirus' named entity 'AEs' named entity 'herbal medicine' named entity '0.01' named entity 'herbal medicine' named entity 'Western medicine' named entity 'case reports' named entity 'Symptom' named entity 'symptom' named entity '1.03' named entity 'lymphocyte' named entity 'Meta-analysis' named entity 'sputum production' named entity 'adverse events' named entity 'clinical studies' named entity 'herbal medicine' named entity 'symptom' named entity 'COVID-19' named entity 'herbal medicine' named entity 'sample size' named entity 'procalcitonin' named entity 'mainland China' named entity 'TCM' named entity 'TCM' named entity 'coronavirus' named entity 'Meta-analysis' named entity 'COVID'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software