About: Characteristics and Clinical Outcomes of COVID‐19 Patients in an Underserved‐Inner City Population: A Single Tertiary Center Cohort

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About: Characteristics and Clinical Outcomes of COVID‐19 Patients in an Underserved‐Inner City Population: A Single Tertiary Center Cohort Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Characteristics and Clinical Outcomes of COVID‐19 Patients in an Underserved‐Inner City Population: A Single Tertiary Center Cohort
Creator	Lo, Albano, Jeri Azmaiparashvili, Zurab Gul, Fahad Pelayo, Jerald Rangaswami, Janani Salacup, Grace Do, Iii Do, Ruchika Kevin, Bryan Patarroyo-Aponte, Gabriel Peterson Do, Eric Benzaquen, Sadia De Joy, Robert
Source	Medline; PMC
abstract	BACKGROUND: There is limited information describing the characteristics and clinical outcomes of patients infected with coronavirus disease 2019 (COVID‐19) especially those in underserved urban area with minority population in the United States. METHODS: This is a retrospective single center study for patients who were admitted with COVID‐19 infection. Data collection was from March 1 through April 24,2020. Demographic, clinical, laboratory, and treatment data were presented using descriptive statistics and frequencies. Chi‐square test and multivariate logistic regression were used to determine association of risk factors and clinical outcomes. RESULTS: A total of 242 inpatients were included with a mean age of 66 ±14.75 (±SD). 50% were female and 70% were African American. Comorbidities included hypertension (74%), diabetes mellitus (49%), and 19% had either COPD or asthma. Older age was associated with higher risk of inpatient death OR 1.056 [95% CI 1.023 to 1.090; p=0.001]. Inpatient mortality occurred in 70% who needed mechanical ventilation (OR: 29.51; 95% CI: 13.28‐65.60; p<0.0001), 58% who required continuous renal replacement therapy/hemodialysis (CRRT/HD) (OR: 6.63; 95% CI: 2.74‐16.05; p<0.0001), and 69% who needed vasopressors (OR: 30.64; 95% CI: 13.56 to 69.20; p<0.0001). Amongst biomarkers of disease severity, only baseline CRP levels (145±116 mg/L) were associated with mortality OR 1.008 [95% CI 1.003 to 1.012; p=0.002]. CONCLUSION: Majority of hospitalized patients had hypertension and diabetes. Older age was an independent risk factor for inpatient mortality. Requirement of mechanical ventilation, vasopressor use, and CRRT/HD were associated significantly with inpatient mortality. Higher baseline CRP was significantly associated with inpatient death. This article is protected by copyright. All rights reserved.
has issue date	2020-07-03(xsd:dateTime)
bibo:doi	10.1002/jmv.26252
bibo:pmid	32617986
has license	no-cc
sha1sum (hex)	4d9cd7d32567157b7a64fa77ae0e72288f1855ae
schema:url	https://doi.org/10.1002/jmv.26252
resource representing a document's title	Characteristics and Clinical Outcomes of COVID‐19 Patients in an Underserved‐Inner City Population: A Single Tertiary Center Cohort
has PubMed Central identifier	PMC7361748
has PubMed identifier	32617986
schema:publication	J Med Virol
resource representing a document's body	covid:4d9cd7d32567157b7a64fa77ae0e72288f1855ae#body_text
is schema:about of	named entity 'infected' named entity 'COVID-19' named entity 'URBAN AREA' named entity 'POPULATION' named entity 'coronavirus disease 2019' named entity 'United States' named entity 'urban area' named entity 'COVID' named entity 'diabetes mellitus' named entity 'study population' named entity 'respiratory failure' named entity 'IRB' named entity 'New York' named entity 'comorbidities' named entity 'CRRT' named entity 'Bhatraju' named entity 'comorbidity' named entity 'logistic regression' named entity 'COVID-19 pandemic' named entity 'statistically significantly' named entity 'clinical outcomes' named entity 'methylprednisolone' named entity 'mechanical ventilation' named entity 'clinical outcomes' named entity 'multiorgan failure' named entity 'pressor' named entity 'COVID' named entity 'COVID' named entity 'Demographic' named entity 'descriptive statistics' named entity 'African Americans' named entity 'comorbidities' named entity 'Multivariate regression' named entity 'chronic respiratory disease' named entity 'Il-6' named entity 'sample population' named entity 'diabetes' named entity 'single center' named entity 'obesity' named entity 'CRRT' named entity 'clinical outcomes' named entity 'vasopressors' named entity 'selection bias' named entity 'mechanical ventilation' named entity 'continuous variable' named entity 'retrospective cohort' named entity 'data analysis' named entity 'polymerase chain reaction' named entity 'statistically significant' named entity 'vasopressor' named entity 'hydroxychloroquine' named entity 'prognostication' named entity 'diabetes' named entity 'CRRT' named entity 'obese' named entity 'diabetes mellitus' named entity 'COVID' named entity 'hypertension' named entity 'significant difference' named entity 'COVID-19' named entity 'inflammatory response' named entity 'hydroxychloroquine' named entity 'clinical trial' named entity 'intubated' named entity 'Wuhan' named entity 'cell-mediated immune response' named entity 'clinical outcomes' named entity 'respiratory support'

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