About: Clinical evaluation methods for new antimicrobial agents to treat respiratory infections: Report of the Committee for the Respiratory System, Japan Society of Chemotherapy

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About: Clinical evaluation methods for new antimicrobial agents to treat respiratory infections: Report of the Committee for the Respiratory System, Japan Society of Chemotherapy Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Clinical evaluation methods for new antimicrobial agents to treat respiratory infections: Report of the Committee for the Respiratory System, Japan Society of Chemotherapy
Creator	Koga, H Kusano, · Miki, F Niki, Y Oizumi, K Rikitomi, N Saito, A Watanabe, A
Source	Elsevier; Medline; PMC
abstract	Abstract The present report constitutes an attempt to improve and modify the existing clinical evaluation method for new antimicrobial agents to treat respiratory infections. One year ago, a general guideline on the clinical evaluation of antimicrobial agents to treat respiratory infections was drafted in Japanese, leaving scope for critical discussion, and this has been translated into English, as there were no major changes. In this report, respiratory infections have been discussed under the headings “acute respiratory tract infection” and pneumonia and acute exacerbation of chronic pulmonary diseases. Standardized criteria were set for the assessment of severity of infection and effectiveness of the antimicrobial agent in question. Severity was evaluated on the basis of a combined assessment of the severity of infection and severity of the clinical condition of the patients. Clinical effectiveness of the antimicrobial agent used was evaluated on the basis of clinical outcome as well as microbiological outcome of the trial. Body temperature, local pain, cough, change in sputum quality, peripheral white blood cell count, C-reactive protein level, and chest radiograph were used as the parameters for the evaluation. To maintain the quality of specimens to be examined, Geckler's classification of specimens was used. This report was constructed based on the analysis of large amounts of material collected over the years, incorporating internal and external factors concerning the present evaluation methods. The newly suggested standardized criteria for clinical evaluation of the new antimicrobial drugs are expected to be practiced properly hereupon and subjected to further improvement if necessary.
has issue date	1999-12-31(xsd:dateTime)
bibo:doi	10.1007/s101560050020
bibo:pmid	11810502
has license	els-covid
sha1sum (hex)	4ce99f6e680c84e0f140256290cfe958273fac7a
schema:url	https://doi.org/10.1007/s101560050020
resource representing a document's title	Clinical evaluation methods for new antimicrobial agents to treat respiratory infections: Report of the Committee for the Respiratory System, Japan Society of Chemotherapy
has PubMed Central identifier	PMC7128963
has PubMed identifier	11810502
schema:publication	Journal of Infection and Chemotherapy
resource representing a document's body	covid:4ce99f6e680c84e0f140256290cfe958273fac7a#body_text
is schema:about of	named entity 'chronic' named entity 'expected' named entity 'condition' named entity 'agents' named entity 'set' named entity 'ANTIMICROBIAL DRUGS' named entity 'EVALUATION METHODS' named entity 'LEAVING' named entity 'AMOUNTS' named entity 'RESPIRATORY TRACT INFECTION' named entity 'ANALYSIS' named entity 'CHANGE IN' named entity 'IMPROVEMENT' named entity 'MATERIAL' named entity 'CLINICAL EVALUATION' named entity 'PNEUMONIA' named entity 'TRANSLATED' named entity 'PRACTICED' named entity 'EVALUATION METHOD' named entity 'ANTIMICROBIAL AGENTS' named entity 'LOCAL' named entity 'COMBINED' named entity 'NEWLY' named entity 'ACUTE EXACERBATION' named entity 'EXPECTED' named entity 'PATIENTS' named entity 'TO MAINTAIN' named entity 'EVALUATED' named entity 'JAPANESE' named entity 'CHEST RADIOGRAPH' named entity 'GUIDELINE' named entity 'YEARS' named entity 'QUESTION' named entity 'CRITICAL' named entity 'PAIN' named entity 'CHRONIC' named entity 'HAVE' named entity 'GENERAL' named entity 'LARGE' named entity 'ONE YEAR AGO' named entity 'PRESENT' named entity 'RESPIRATORY INFECTIONS' named entity 'TRIAL' named entity 'CHANGES' named entity 'COLLECTED' named entity 'TREAT' named entity 'TO BE EXAMINED' named entity 'REPORT' named entity 'USED' named entity 'MICRO-' named entity 'CONSTRUCTED' named entity 'SET' named entity 'BASED' named entity 'PERIPHERAL' named entity 'OUTCOME' named entity 'ANTIMICROBIAL AGENT' named entity 'ATTEMPT' named entity 'EFFECTIVENESS' named entity 'QUALITY' named entity 'BASIS' named entity 'MAJOR' named entity 'EXTERNAL' named entity 'C-REACTIVE PROTEIN LEVEL' named entity 'DISCUSSION' named entity 'BIOLOGICAL OUTCOME' named entity 'INTERNAL' named entity 'PARAMETERS' named entity 'COUGH' named entity 'CLASSIFICATION' named entity 'MODIFY' named entity 'ASSESSMENT' named entity 'INFECTION' named entity 'CONDITION' named entity '27S'

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