About: High SARS-CoV-2 Antibody Prevalence among Healthcare Workers Exposed to COVID-19 Patients

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About: High SARS-CoV-2 Antibody Prevalence among Healthcare Workers Exposed to COVID-19 Patients Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	High SARS-CoV-2 Antibody Prevalence among Healthcare Workers Exposed to COVID-19 Patients
Creator	Wang, Jian Liu, Yong Wu, Chao Chen, Yong Huang, Weijin Chen, Yan Chen, Yuxin Huang, Rui Yuan, Ling Huang, Aijun Shen, Han Tong, Xin Yan, Xiaomin Yang, Hailong Yin, Shengxia
Source	Elsevier; Medline; PMC
abstract	The seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was examined among 105 healthcare workers (HCWs) exposed to four patients who were laboratory confirmed with coronavirus disease 2019 (COVID-19), the disease caused by SARS-CoV-2 infection. These HCWs were immediately under quarantine for 14 days as soon as they were identified as close contacts. The nasopharyngeal swab samples were collected on the first and 14(th) day of the quarantine, while the serum samples were obtained on the 14(th) day of the quarantine. With the assay of enzyme immunoassay (EIA) and microneutralization assay, 17.14% (18/105) of HCWs were seropositive, while their swab samples were found to be SARS-CoV-2 RNA negative. Risk analysis revealed that wearing face mask could reduce the infection risk (odds ratio [OR], 0.127, 95% confidence interval [CI] 0.017, 0.968), while when exposed to COVID-19 patients, doctors might have higher risk of seroconversion (OR, 346.837, 95% CI 8.924, 13479.434), compared with HCWs exposed to colleagues as well as nurses and general service assistants who exposed to patients. Our study revealed that the serological testing is useful for the identification of asymptomatic or subclinical infection of SARS-CoV-2 among close contacts with COVID-19 patients.
has issue date	2020-06-04(xsd:dateTime)
bibo:doi	10.1016/j.jinf.2020.05.067
bibo:pmid	32504745
has license	no-cc
sha1sum (hex)	4c89195bdd643fa07f76fa5fbee114cab9877cb6
schema:url	https://doi.org/10.1016/j.jinf.2020.05.067
resource representing a document's title	High SARS-CoV-2 Antibody Prevalence among Healthcare Workers Exposed to COVID-19 Patients
has PubMed Central identifier	PMC7270786
has PubMed identifier	32504745
schema:publication	J Infect
resource representing a document's body	covid:4c89195bdd643fa07f76fa5fbee114cab9877cb6#body_text
is schema:about of	named entity 'coronavirus disease 2019' named entity 'patients' named entity 'COVID-19' named entity 'Healthcare' named entity 'IDENTIFIED' named entity 'SEROPREVALENCE' named entity 'SERUM' named entity 'IMMEDIATELY' named entity 'caused' named entity 'serum' named entity 'infection' named entity 'Workers' named entity 'SARS-CoV-2' named entity 'COVID' named entity 'serum samples' named entity 'quarantine' named entity 'SARS-CoV-2' named entity 'Antibody' named entity 'virus' named entity 'nasopharyngeal swab' named entity 'RBD' named entity 'COVID' named entity 'infection' named entity 'RBD' named entity 'VSV-G' named entity 'seroconversion' named entity 'China' named entity 'surgical masks' named entity 'COVID-19' named entity 'pET' named entity 'polyacrylamide gel electrophoresis' named entity 'face mask' named entity 'IgG' named entity 'Qiagen' named entity 'seroprevalence' named entity 'epidemiological' named entity 'pseudovirus' named entity 'protein' named entity '2, 3' named entity 'SARS-CoV-2' named entity 'SARS-CoV-2' named entity 'confidence interval' named entity 'Nasopharyngeal swab' named entity 'SARS-CoV-2' named entity 'negative control' named entity 'infection' named entity 'viral load' named entity 'myalgia' named entity 'human coronaviruses' named entity 'seropositive' named entity 'VSV' named entity 'RNA' named entity 'sore throat' named entity 'surgical mask' named entity 'face mask' named entity 'nasopharyngeal swab' named entity 'HCW' named entity 'Chi-square test' named entity 'RBD' named entity 'serum' named entity 'RNA' named entity 'SARS-CoV-2' named entity 'SARS-CoV-2' named entity 'public health' named entity 'China' named entity 'quarantine' named entity 'serum samples'

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