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About:
Microsensor Arrays for Saliva Diagnostics
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An Entity of Type :
schema:ScholarlyArticle
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covidontheweb.inria.fr
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Type:
Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
has title
Microsensor Arrays for Saliva Diagnostics
Creator
Bhatia, Jasvinder
Blicharz, Timothy
Bowden, Michaela
Brody, Jerome
Grand-Pierre, Nerline
Hayman, Ryan
Helmerhorst, Eva
Little, Frédéric
Oppenheim, Frank
Rissin, David
Siqueira, Walter
Walt, David
Source
PMC
abstract
abstract: Optical fiber microarrays have been used to screen saliva from patients with end‐stage renal disease (ESRD) to ascertain the efficacy of dialysis. We have successfully identified markers in saliva that correlate with kidney disease. Standard assay chemistries for these markers have been converted to disposable test strips such that patients may one day be able to monitor their clinical status at home. Details of these developments are described. In addition, saliva from asthma and chronic obstructive pulmonary disease (COPD) patients is being screened for useful diagnostic markers. Our goal is to develop a multiplexed assay for these protein and nucleic acid biomarkers for diagnosing the cause and severity of pulmonary exacerbations, enabling more effective treatment to be administered. These results are reported in the second part of this article.
has issue date
2007-04-02
(
xsd:dateTime
)
bibo:doi
10.1196/annals.1384.031
bibo:pmid
17435144
has license
no-cc
sha1sum (hex)
4b87dc1aa0af1c321679f16701d1baec66ffedc9
schema:url
https://doi.org/10.1196/annals.1384.031
resource representing a document's title
Microsensor Arrays for Saliva Diagnostics
has PubMed Central identifier
PMC7168095
has PubMed identifier
17435144
schema:publication
Ann N Y Acad Sci
resource representing a document's body
covid:4b87dc1aa0af1c321679f16701d1baec66ffedc9#body_text
is
schema:about
of
named entity 'acid'
named entity 'converted'
named entity 'efficacy'
named entity 'enabling'
named entity 'Details'
named entity 'kidney disease'
named entity 'Arrays'
named entity 'microarrays'
named entity 'particulate matter'
named entity 'BUMC'
named entity 'humidity'
named entity 'correlate'
named entity 'Saliva'
named entity 'biomarkers'
named entity 'chronic obstructive pulmonary disease'
named entity 'assay'
named entity 'asthma'
named entity 'saliva'
named entity 'end-stage renal disease'
named entity 'IFN'
named entity 'ESRD'
named entity 'oligonucleotide microarray'
named entity 'pathogens'
named entity 'pathogen'
named entity 'clinical complications'
named entity 'asthma'
named entity 'saliva samples'
named entity 'biomarkers'
named entity 'saliva'
named entity 'Cy3'
named entity 'inflammatory state'
named entity 'dialysis'
named entity 'ESRD'
named entity 'pathogens'
named entity 'Fluorescence'
named entity 'sodium'
named entity 'Illumina, Inc.'
named entity 'nucleic acid detection'
named entity 'nucleic acids'
named entity 'streptavidin'
named entity 'correlation'
named entity 'sodium'
named entity 'dialysis treatment'
named entity 'analyte'
named entity 'covalent'
named entity 'microsphere'
named entity 'saliva'
named entity 'time intervals'
named entity 'infection'
named entity 'statistically significant'
named entity 'inflammatory diseases'
named entity 'microsphere'
named entity 'multiplexed'
named entity 'inflammation'
named entity 'COPD'
named entity 'asthma'
named entity 'asthmatics'
named entity 'cytokines'
named entity 'chemokine'
named entity 'fluorescent'
named entity 'VEGF'
named entity 'Dialysis'
named entity 'chemokines'
named entity 'salivary protein'
named entity 'blood testing'
named entity 'viral infection'
named entity 'San Diego'
named entity 'microfluidics'
named entity 'asthma'
named entity 'pathogen'
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