About: Application of Healthcare ‘Big Data’ in CNS Drug Research: The Example of the Neurological and mental health Global Epidemiology Network (NeuroGEN)

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About: Application of Healthcare ‘Big Data’ in CNS Drug Research: The Example of the Neurological and mental health Global Epidemiology Network (NeuroGEN) Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Application of Healthcare ‘Big Data’ in CNS Drug Research: The Example of the Neurological and mental health Global Epidemiology Network (NeuroGEN)
Creator	Chan, Adrienne Wong, Ian Lau, C Li, · Chan, Esther Kim, Hwan Kenneth, · Brauer, Ruth Cook, Sharon Crystal, Stephen De Paoli, Giorgia Edu, Jenni Frederick, · Hao Luo, · Hartikainen, Sirpa Ho, K Ilomäki, Jenni Ju, · Klungel, Olaf Koponen, Marjaana Kui, · Lai, Chia-Cheng Lau, Kai Lorenna, · Lum, Y Man, K Marloes Bazelier, · Pajouheshnia, Romin Pell, Jill Rooke, Evelien Setoguchi, Soko Shen, Chin-Yao Shin, Ju-Young Simon Bell, · Terry, · Tolppanen, Anna-Maija Wallis, ·
source	PMC
abstract	Neurological and psychiatric (mental health) disorders have a large impact on health burden globally. Cognitive disorders (including dementia) and stroke are leading causes of disability. Mental health disorders, including depression, contribute up to one-third of total years lived with disability. The Neurological and mental health Global Epidemiology Network (NeuroGEN) is an international multi-database network that harnesses administrative and electronic medical records from Australia, Asia, Europe and North America. Using these databases NeuroGEN will investigate medication use and health outcomes in neurological and mental health disorders. A key objective of NeuroGEN is to facilitate high-quality observational studies to address evidence-practice gaps where randomized controlled trials do not provide sufficient information on medication benefits and risks that is specific to vulnerable population groups. International multi-database research facilitates comparisons across geographical areas and jurisdictions, increases statistical power to investigate small subpopulations or rare outcomes, permits early post-approval assessment of safety and effectiveness, and increases generalisability of results. Through bringing together international researchers in pharmacoepidemiology, NeuroGEN has the potential to be paradigm-changing for observational research to inform evidence-based prescribing. The first focus of NeuroGEN will be to address evidence-gaps in the treatment of chronic comorbidities in people with dementia.
has issue date	2020-06-22(xsd:dateTime)
bibo:doi	10.1007/s40263-020-00742-4
has license	no-cc
sha1sum (hex)	4a09ca1d4fd34e19d6c66f7a6c8d736e4ca36677
schema:url	https://doi.org/10.1007/s40263-020-00742-4
resource representing a document's title	Application of Healthcare ‘Big Data’ in CNS Drug Research: The Example of the Neurological and mental health Global Epidemiology Network (NeuroGEN)
has PubMed Central identifier	PMC7306570
schema:publication	CNS Drugs
resource representing a document's body	covid:4a09ca1d4fd34e19d6c66f7a6c8d736e4ca36677#body_text
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