About: Structural Genomics of SARS-CoV-2 Indicates Evolutionary Conserved Functional Regions of Viral Proteins

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Structural Genomics of SARS-CoV-2 Indicates Evolutionary Conserved Functional Regions of Viral Proteins
Creator	Liu, Ming Cui, Hongzhu Gao, Ziyang Korkin, Dmitry Lu, Senbao Mkandawire, Winnie Narykov, Oleksandr Srinivasan, Suhas Sun, Mo
Source	Medline; PMC
abstract	During its first two and a half months, the recently emerged 2019 novel coronavirus, SARS-CoV-2, has already infected over one-hundred thousand people worldwide and has taken more than four thousand lives. However, the swiftly spreading virus also caused an unprecedentedly rapid response from the research community facing the unknown health challenge of potentially enormous proportions. Unfortunately, the experimental research to understand the molecular mechanisms behind the viral infection and to design a vaccine or antivirals is costly and takes months to develop. To expedite the advancement of our knowledge, we leveraged data about the related coronaviruses that is readily available in public databases and integrated these data into a single computational pipeline. As a result, we provide comprehensive structural genomics and interactomics roadmaps of SARS-CoV-2 and use this information to infer the possible functional differences and similarities with the related SARS coronavirus. All data are made publicly available to the research community.
has issue date	2020-03-25(xsd:dateTime)
bibo:doi	10.3390/v12040360
bibo:pmid	32218151
has license	cc-by
sha1sum (hex)	4950ceced634366595957f29d6045827c98f12bc
schema:url	https://doi.org/10.3390/v12040360
resource representing a document's title	Structural Genomics of SARS-CoV-2 Indicates Evolutionary Conserved Functional Regions of Viral Proteins
has PubMed Central identifier	PMC7232164
has PubMed identifier	32218151
schema:publication	Viruses
resource representing a document's body	covid:4950ceced634366595957f29d6045827c98f12bc#body_text
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