About: Viral RNA load and histological changes in tissues following experimental infection with an arterivirus of possums (wobbly possum disease virus)

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Viral RNA load and histological changes in tissues following experimental infection with an arterivirus of possums (wobbly possum disease virus) Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Viral RNA load and histological changes in tissues following experimental infection with an arterivirus of possums (wobbly possum disease virus)
Creator	Aberdein, Danielle Dunowska, Magdalena Giles, Julia Morel, Patrick Perrott, Matthew Roe, Wendi Shrestha, Kshitiz
Source	Elsevier; Medline; PMC
abstract	Abstract Tissues from Australian brushtail possums (Trichosurus vulpecula) that had been experimentally infected with wobbly possum disease (WPD) virus (WPDV) were examined to elucidate pathogenesis of WPDV infection. Mononuclear inflammatory cell infiltrates were present in livers, kidneys, salivary glands and brains of WPD-affected possums. Specific staining was detected by immunohistochemistry within macrophages in the livers and kidneys, and undefined cell types in the brains. The highest viral RNA load was found in macrophage-rich tissues. The detection of viral RNA in the salivary gland, serum, kidney, bladder and urine is compatible with transmission via close physical contact during encounters such as fighting or grooming, or by contact with an environment that has been contaminated with saliva or urine. Levels of viral RNA remained high in all tissues tested throughout the study, suggesting that on-going virus replication and evasion of the immune responses may be important in the pathogenesis of disease.
has issue date	2018-09-30(xsd:dateTime)
bibo:doi	10.1016/j.virol.2018.07.003
bibo:pmid	30014860
has license	els-covid
sha1sum (hex)	48260641211ab08d7f061d905f78a1313f5b66ed
schema:url	https://doi.org/10.1016/j.virol.2018.07.003
resource representing a document's title	Viral RNA load and histological changes in tissues following experimental infection with an arterivirus of possums (wobbly possum disease virus)
has PubMed Central identifier	PMC7126967
has PubMed identifier	30014860
schema:publication	Virology
resource representing a document's body	covid:48260641211ab08d7f061d905f78a1313f5b66ed#body_text
is schema:about of	named entity 'LOAD' named entity 'disease' named entity 'EXPERIMENTAL INFECTION' named entity 'ARTERIVIRUS' named entity 'CHANGES' named entity 'VIRAL RNA' named entity 'HISTOLOGICAL' named entity 'TISSUES' named entity 'DISEASE VIRUS' named entity 'POSSUM' named entity 'FOLLOWING' named entity 'infection' named entity 'RNA' named entity 'infection' named entity 'digital camera' named entity 'virus' named entity 'chromogen' named entity 'organ' named entity 'azotaemia' named entity 'histological' named entity 'kidney' named entity 'urinary excretion' named entity 'body fluid' named entity 'antibody' named entity 'RNA' named entity 'macrophages' named entity 'neurological signs' named entity 'RNA' named entity 'antibody' named entity 'nucleocapsid' named entity 'virus' named entity 'incubation' named entity 'virus replication' named entity 'infection' named entity 'spleen' named entity 'recombinant' named entity 'serum' named entity 'synechiae' named entity 'hindbrain' named entity 'serum samples' named entity 'Direct contact' named entity 'monocytes' named entity 'infection' named entity 'infection' named entity 'kidney' named entity 'macrophages' named entity 'phosphate' named entity 'Tween 20' named entity 'hepatic' named entity 'Western blot' named entity 'protein' named entity 'immunohistochemistry' named entity 'macrophages' named entity 'serum' named entity 'azotaemia' named entity 'salivary glands' named entity 'antigen' named entity 'immune response' named entity 'serum' named entity 'porcine reproductive and respiratory syndrome virus' named entity 'qPCR' named entity 'forebrain' named entity 'homogenates' named entity 'forebrain' named entity 'urine' named entity 'CNS' named entity 'endothelial cell' named entity 'RNA' named entity 'hyperplasia' named entity 'RNA' named entity 'bladder' named entity 'body fluids' named entity 'kidney' named entity 'endothelium' named entity 'SAS software'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software