About: Molecular characterization of adenoviral infections in Cuba: report of an unusual association of species D adenoviruses with different clinical syndromes

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About: Molecular characterization of adenoviral infections in Cuba: report of an unusual association of species D adenoviruses with different clinical syndromes Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Molecular characterization of adenoviral infections in Cuba: report of an unusual association of species D adenoviruses with different clinical syndromes
Creator	Ae, Ma Belsy, Acosta Clara, Savón Inmaculada, Casas Luis, Sarmiento Ae Gonzalez, Angel Ae Gonzalez, Grehete Ae, Alexander Ae, Alina Ae, Guelsys Ae, Odalys Ae, Pedro Alexander, Á Angel, Á Belsy, A Breñ, Perez Clara, Á Goyenechea, A Grehete, Á Guadalupe, G Guelsys, Á Llop, Guadalupe Luis, S María, Guzmán Más, A Odalys, V Pedro, Á Pilar, P Valdés, A
Source	Medline; PMC
abstract	Adenoviruses are common pathogens that are responsible for a wide variety of infectious syndromes. The objectives of this study were to identify and characterize members of different adenovirus species at the molecular level and to describe the correlation between viruses and clinical syndromes during a period of 4 years. Between 2002 and 2006, 45 of 512 respiratory specimens (8%) from patients with acute respiratory tract infection tested positive for adenovirus. Four adenovirus isolates from samples sent for enterovirus isolation were also analyzed. This research identified 49 confirmed cases of human adenovirus infection by PCR and/or viral culture. The most common diagnosis was upper respiratory infection (44%). Human adenovirus D was the major species found (59%), followed by Human adenovirus C (36%) and Human adenovirus B (4%). Human adenovirus 5 was the major serotype found producing bronchiolitis, followed by human adenovirus 6. In patients with upper respiratory infection, the major serotype found was human adenovirus 17. Viruses of the species Human adenovirus D were identified in seven (77%) cases of acute febrile syndrome. Four isolates from clinical materials obtained from patients with encephalitis, acute flaccid paralysis and meningoencephalitis were identified as belonging to the species Human adenovirus D. Our data demonstrate a surprising result about the identification of an unusual association of viruses of the species Human adenovirus D with different clinical syndromes. This observation could be evaluated as a possible indicator of the emergence of a novel strain but further studies are required.
has issue date	2009-03-12(xsd:dateTime)
bibo:doi	10.1007/s00705-009-0338-4
bibo:pmid	19280320
has license	no-cc
sha1sum (hex)	465dbf79b3406de602dd16228f8c071abd53d9e5
schema:url	https://doi.org/10.1007/s00705-009-0338-4
resource representing a document's title	Molecular characterization of adenoviral infections in Cuba: report of an unusual association of species D adenoviruses with different clinical syndromes
has PubMed Central identifier	PMC7086751
has PubMed identifier	19280320
schema:publication	Arch Virol
resource representing a document's body	covid:465dbf79b3406de602dd16228f8c071abd53d9e5#body_text
is schema:about of	named entity 'isolates' named entity 'acute flaccid paralysis' named entity 'producing' named entity 'serotype' named entity 'adenovirus' named entity 'identified' named entity 'adenovirus' named entity 'ASSOCIATION' named entity 'DIFFERENT' named entity 'OBTAINED' named entity 'DIFFERENT' named entity 'HUMAN ADENOVIRUS 17' named entity 'OBJECTIVES' named entity 'ADENOVIRUSES' named entity 'WIDE' named entity 'HUMAN ADENOVIRUS 6' named entity 'RESEARCH' named entity 'FEBRILE' named entity 'SEVEN' named entity 'HUMAN ADENOVIRUS' named entity 'HUMAN ADENOVIRUS 5' named entity 'UPPER RESPIRATORY INFECTION' named entity 'IDENTIFICATION' named entity 'HUMAN ADENOVIRUS D' named entity 'REQUIRED' named entity 'HUMAN ADENOVIRUS B' named entity 'ISOLATES' named entity '288' named entity 'ACUTE' named entity 'MENINGOENCEPHALITIS' named entity 'MAJOR' named entity 'DATA' named entity 'TESTED' named entity 'FOLLOWED BY' named entity 'BUT' named entity 'VIRUSES' named entity 'BELONGING' named entity 'NOVEL' named entity 'ACUTE FLACCID PARALYSIS' named entity 'EMERGENCE' named entity 'POSSIBLE' named entity 'MOLECULAR' named entity 'COULD BE' named entity 'EVALUATED' named entity 'LEVEL' named entity 'UNUSUAL' named entity 'PATIENTS' named entity 'CLINICAL' named entity '512' named entity 'SEROTYPE' named entity 'INFECTIOUS' named entity 'MOLECULAR' named entity 'CUBA'

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