About: The central role of chloride in the metabolic acid–base changes in canine parvoviral enteritis

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: The central role of chloride in the metabolic acid–base changes in canine parvoviral enteritis Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The central role of chloride in the metabolic acid–base changes in canine parvoviral enteritis
Creator	Burchell, Richard Leisewitz, Andrew Schoeman, Johan
Source	Elsevier; Medline; PMC
abstract	Abstract The acid–base disturbances in canine parvoviral (CPV) enteritis are not well described. In addition, the mechanisms causing these perturbations have not been fully elucidated. The purpose of the present study was to assess acid–base changes in puppies suffering from CPV enteritis, using a modified strong ion model (SIM). The hypothesis of the study was that severe acid–base disturbances would be present and that the SIM would provide insights into pathological mechanisms, which have not been fully appreciated by the Henderson–Hasselbalch model. The study analysed retrospective data, obtained from 42 puppies with confirmed CPV enteritis and 10 healthy control dogs. The CPV-enteritis group had been allocated a clinical score, to allow classification of the data according to clinical severity. The effects of changes in free water, chloride, l-lactate, albumin and phosphate were calculated, using a modification of the base excess algorithm. When the data were summated for each patient, and correlated to each individual component, the most important contributor to the metabolic acid–base changes, according to the SIM, was chloride (P <0.001). Severely-affected animals tended to demonstrate hypochloraemic alkalosis, whereas mildly-affected puppies had a hyperchloraemic acidosis (P =0.007). In conclusion, the acid–base disturbances in CPV enteritis are multifactorial and complex, with the SIM providing information in terms of the origin of these changes.
has issue date	2014-04-30(xsd:dateTime)
bibo:doi	10.1016/j.tvjl.2014.01.017
bibo:pmid	24613416
has license	els-covid
sha1sum (hex)	444139f42a123635d16c1a93223a40a1dbd1b188
schema:url	https://doi.org/10.1016/j.tvjl.2014.01.017
resource representing a document's title	The central role of chloride in the metabolic acid–base changes in canine parvoviral enteritis
has PubMed Central identifier	PMC7128572
has PubMed identifier	24613416
schema:publication	The Veterinary Journal
resource representing a document's body	covid:444139f42a123635d16c1a93223a40a1dbd1b188#body_text
is schema:about of	named entity 'ACID' named entity 'BASE' named entity 'hypothesis' named entity 'canine' named entity 'CENTRAL' named entity 'CANINE' named entity 'CHANGES' named entity 'SEVERE' named entity 'PURPOSE' named entity 'ASSESS' named entity 'CPV' named entity 'CAUSING' named entity 'MODEL' named entity 'HENDERSON' named entity 'PRESENT' named entity 'CHANGES' covid:arg/444139f42a123635d16c1a93223a40a1dbd1b188 named entity 'ACID' named entity 'BASE' named entity 'CHLORIDE' named entity 'METABOLIC' named entity 'ROLE' named entity 'ENTERITIS' named entity 'HAVE' named entity 'DESCRIBED' named entity 'SIM' named entity 'PUPPIES' named entity 'SUFFERING' named entity 'ADDITION' named entity 'PROVIDE' named entity 'HYPOTHESIS' named entity 'USING' named entity 'PATHOLOGICAL' named entity 'STRONG' named entity 'MODIFIED' named entity 'INSIGHTS' named entity 'NOT WELL' named entity 'ION' named entity 'FULLY' named entity 'MECHANISMS' named entity 'CANINE' named entity 'STUDY' named entity 'THESE' named entity 'ENTERITIS' named entity 'ion' named entity 'strong' named entity 'enteritis' named entity 'canine' named entity 'ion' named entity 'alkalosis' named entity 'rank correlation' named entity 'acidosis' named entity 'vomiting' named entity 'diarrhoea' named entity 'alkalosis' named entity 'acidosis' named entity 'ion' named entity 'control group' named entity 'plasma protein' named entity 'acid-base disturbances' named entity 'base excess' named entity 'biomarkers' named entity 'base excess' named entity 'acidity or alkalinity' named entity 'control group' named entity 'total protein' named entity 'base excess' named entity 'alkalosis' named entity 'albumin' named entity 'metabolic' named entity 'acidosis' named entity 'electron microscopy' named entity 'anions' named entity 'acid-base' named entity 'acidosis' named entity 'control group' named entity 'acid-base' named entity 'Mann-Whitney U test' named entity 'L-lactate'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software