About: Respiratory support by neurally adjusted ventilatory assist (NAVA) in severe RSV-related bronchiolitis: a case series report

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About: Respiratory support by neurally adjusted ventilatory assist (NAVA) in severe RSV-related bronchiolitis: a case series report Goto Sponge NotDistinct Permalink

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Respiratory support by neurally adjusted ventilatory assist (NAVA) in severe RSV-related bronchiolitis: a case series report
Creator	Bétrémieux, Pierre Dejode, Jean-Marc Joram, Nicolas Liet, Jean-Michel Rozé, Jean-Christophe Gaillard-Le Roux, Bénédicte
Source	PMC
abstract	BACKGROUND: Neurally adjusted ventilatory assist (NAVA) is a new mode of mechanical ventilation controlled by diaphragmatic electrical signals. The electrical signals allow synchronization of ventilation to spontaneous breathing efforts of a child, as well as permitting pressure assistance proportional to the electrical signal. NAVA provides equally fine synchronization of respiratory support and pressure assistance varying with the needs of the child. NAVA has mainly been studied in children who underwent cardiac surgery during the period of weaning from a respirator. CASE PRESENTATION: We report here a series of 3 children (1 month, 3 years, and 28 days old) with severe respiratory distress due to RSV-related bronchiolitis requiring invasive mechanical ventilation with a high level of oxygen (FiO(2 )≥50%) for whom NAVA facilitated respiratory support. One of these children had diagnosis criteria for acute lung injury, another for acute respiratory distress syndrome. Establishment of NAVA provided synchronization of mechanical ventilatory support with the breathing efforts of the children. Respiratory rate and inspiratory pressure became extremely variable, varying at each cycle, while children were breathing easily and smoothly. All three children demonstrated less oxygen requirements after introducing NAVA (57 ± 6% to 42 ± 18%). This improvement was observed while peak airway pressure decreased (28 ± 3 to 15 ± 5 cm H(2)O). In one child, NAVA facilitated the management of acute respiratory distress syndrome with extensive subcutaneous emphysema. CONCLUSIONS: Our findings highlight the feasibility and benefit of NAVA in children with severe RSV-related bronchiolitis. NAVA provides a less aggressive ventilation requiring lower inspiratory pressures with good results for oxygenation and more comfort for the children.
has issue date	2011-10-20(xsd:dateTime)
bibo:doi	10.1186/1471-2431-11-92
bibo:pmid	22014152
has license	cc-by
sha1sum (hex)	4313564fec59facf82281a6de7eb1b690603daa9
schema:url	https://doi.org/10.1186/1471-2431-11-92
resource representing a document's title	Respiratory support by neurally adjusted ventilatory assist (NAVA) in severe RSV-related bronchiolitis: a case series report
has PubMed Central identifier	PMC3207882
has PubMed identifier	22014152
schema:publication	BMC Pediatr
resource representing a document's body	covid:4313564fec59facf82281a6de7eb1b690603daa9#body_text
is schema:about of	named entity 'cycle' named entity 'child' named entity 'demonstrated' named entity 'cardiac surgery' named entity 'introducing' named entity 'high level' named entity 'acute lung injury' named entity 'ventilation' named entity 'observed' named entity 'SUPPORT' named entity 'INSPIRATORY' named entity 'SIGNALS' named entity 'VARIABLE' named entity 'MECHANICAL VENTILATION' named entity 'All' named entity 'NAVA' named entity 'NAVA' named entity 'NAVA' named entity 'series' named entity 'mechanical ventilation' named entity 'electrical signal' named entity 'electrical signals' named entity 'synchronization' named entity 'pressure' named entity 'case series' named entity 'bronchiolitis' named entity 'severe' named entity 'Respiratory rate' named entity 'acute respiratory distress syndrome' named entity 'oxygen' named entity 'inspiratory pressure' named entity 'NAVA' named entity 'NAVA' named entity 'respirator' named entity 'respiratory support' named entity 'NAVA' named entity 'bronchiolitis' named entity 'NAVA' named entity 'respiratory rate' named entity 'acute respiratory distress syndrome' named entity 'respiratory distress' named entity 'clinical practice' named entity 'NAVA' named entity 'RSV' named entity 'cough' named entity 'NAVA' named entity 'mechanical ventilation' named entity 'lungs' named entity 'ARDS' named entity 'NAVA' named entity '3.8' named entity 'aspirate' named entity 'diaphragm' named entity 'NAVA' named entity 'blood gases' named entity 'NAVA' named entity 'weaning' named entity 'blood pH' named entity 'extubation' named entity 'sedation' named entity 'respiratory distress' named entity 'sedation' named entity 'intubated' named entity 'CPAP' named entity 'minute volume' named entity 'subcutaneous emphysema' named entity 'peak inspiratory pressure' named entity 'NAVA' named entity 'electrical signals' named entity 'pneumothorax' named entity 'mechanical ventilation' named entity 'botulism' named entity 'respirator' named entity 'bradycardia' named entity 'positive end-expiratory pressure' named entity 'pulmonary gas exchange'

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