About: Antiviral Potential of Selected Starter Cultures, Bacteriocins and d,l-Lactic Acid

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Antiviral Potential of Selected Starter Cultures, Bacteriocins and d,l-Lactic Acid
Creator	Albert, • Braun, • Fehlhaber, • Lange-Starke, Anett Petereit, • Truyen, •
Source	Medline; PMC
abstract	The antiviral potential of selected bacteria species [lactic acid bacteria (LAB) and micrococcaceae] was examined. By this, the effect of their cell-free supernatants as well as of certain species-related metabolites (sakacin A, nisin, and lactic acid) was investigated on different viruses after exposure at 24 °C for 3 days. Viruses were incubated with supernatants and metabolites in a dilution ratio of 1:10. Data for antiviral effects towards murine norovirus S99 (MNV), influenza A virus A/WSN/33 (H1N1), Newcastle disease virus Montana (NDV) and feline herpesvirus KS 285 (FHV) were generated in vitro simulating pH and temperature conditions according to raw sausage fermentations. Investigations showed no antiviral effect of sakacin A and nisin on MNV, H1N1, FHV and NDV. Furthermore, the antiviral potential of d,l-lactic acid was determined for MNV and H1N1. At raw sausage-related pH values (5.0–6.2) it could be shown that the virus titre for MNV and H1N1 was reduced by a maximum of 3.25 log and 2.5 log units, respectively. In addition, 29 culture supernatants of different bacteria species, mainly LAB and staphylococci, were tested for their antiviral activity against MNV. Only the cell-free supernatant of a Lb. curvatus strain showed a higher virus titre reduction of MNV by 1.25 log units compared to the control. Further studies on the characterisation of this cell-free supernatant were carried out, however, the antiviral substance could not be identified so far.
has issue date	2013-12-03(xsd:dateTime)
bibo:doi	10.1007/s12560-013-9135-z
bibo:pmid	24297091
has license	no-cc
sha1sum (hex)	42a62508a80a3b11a1195ee0349c29d9d9548baa
schema:url	https://doi.org/10.1007/s12560-013-9135-z
resource representing a document's title	Antiviral Potential of Selected Starter Cultures, Bacteriocins and d,l-Lactic Acid
has PubMed Central identifier	PMC7090810
has PubMed identifier	24297091
schema:publication	Food Environ Virol
resource representing a document's body	covid:42a62508a80a3b11a1195ee0349c29d9d9548baa#body_text
is schema:about of	named entity 'compared' named entity 'supernatant' named entity 'activity' named entity 'potential' named entity 'influenza A virus' named entity 'bacteria' named entity 'CULTURES' named entity 'DAYS' named entity 'FELINE HERPESVIRUS' named entity 'CULTURE' named entity 'LOG' named entity 'DATA' named entity 'CERTAIN' named entity 'GENERATED' named entity 'STRAIN' named entity 'STUDIES' named entity 'CONTROL' named entity 'ADDITION' named entity 'TEMPERATURE' named entity 'SIMULATING' named entity 'NISIN' named entity 'ACCORDING' named entity 'RAW' named entity 'IDENTIFIED' named entity 'VALUES' named entity 'ANTIVIRAL ACTIVITY' named entity 'SUBSTANCE' named entity 'SAKACIN A' named entity 'SELECTED' named entity 'FAR' named entity 'COMPARED' named entity 'HIGHER' named entity 'FREE' covid:arg/42a62508a80a3b11a1195ee0349c29d9d9548baa named entity 'MNV' named entity 'MICROCOCCACEAE' named entity 'CONDITIONS' named entity 'BACTERIOCINS' named entity 'ANTIVIRAL' named entity 'DILUTION RATIO' named entity 'DETERMINED' named entity 'SELECTED' named entity 'IN VITRO' named entity 'INVESTIGATIONS' named entity 'ANTIVIRAL' named entity 'EXPOSURE' named entity 'S99' named entity 'LAB' named entity 'DIFFERENT' named entity 'VIRUS' named entity 'BACTERIA ' named entity 'LACTIC ACID' named entity 'FHV' named entity 'POTENTIAL' named entity 'INFLUENZA A VIRUS' named entity 'RELATED' named entity 'EFFECT' named entity 'TITRE' named entity 'REDUCED' named entity 'VIRUSES' named entity 'TESTED FOR' named entity '6.2' named entity 'MONTANA' named entity 'SUPERNATANT' named entity 'REDUCTION' named entity '1.25' named entity 'ACID' named entity 'H1N1' named entity 'CELL' named entity '2.5' named entity 'CARRIED' named entity 'FERMENTATIONS' named entity 'INCUBATED' named entity 'SPECIES' named entity 'MAXIMUM' named entity 'INVESTIGATED'

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