About: Persistent digestive disorders in the tropics: causative infectious pathogens and reference diagnostic tests

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Persistent digestive disorders in the tropics: causative infectious pathogens and reference diagnostic tests Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Persistent digestive disorders in the tropics: causative infectious pathogens and reference diagnostic tests
Creator	Chappuis, François Lutumba, Pascal Bottieau, Emmanuel Panning, Marcus Boelaert, Marleen Jacobs, Jan Knopp, Stefanie Marti, Hanspeter Meyanti, Fransiska Polman, Katja Rijal, Suman Sacko, Moussa Utzinger, Jürg Vogt, Jürg Becker, Sören Miles, Michael N'goran, K Van Lieshout, Lisette Von Müller, Lutz Warhurst, David Yansouni, Cedric
Source	Medline; PMC
abstract	BACKGROUND: Persistent digestive disorders account for considerable disease burden in the tropics. Despite advances in understanding acute gastrointestinal infections, important issues concerning epidemiology, diagnosis, treatment and control of most persistent digestive symptomatologies remain to be elucidated. Helminths and intestinal protozoa are considered to play major roles, but the full extent of the aetiologic spectrum is still unclear. We provide an overview of pathogens causing digestive disorders in the tropics and evaluate available reference tests. METHODS: We searched the literature to identify pathogens that might give rise to persistent diarrhoea, chronic abdominal pain and/or blood in the stool. We reviewed existing laboratory diagnostic methods for each pathogen and stratified them by (i) microscopy; (ii) culture techniques; (iii) immunological tests; and (iv) molecular methods. Pathogen-specific reference tests providing highest diagnostic accuracy are described in greater detail. RESULTS: Over 30 pathogens may cause persistent digestive disorders. Bacteria, viruses and parasites are important aetiologic agents of acute and long-lasting symptomatologies. An integrated approach, consisting of stool culture, microscopy and/or specific immunological techniques for toxin, antigen and antibody detection, is required for accurate diagnosis of bacteria and parasites. Molecular techniques are essential for sensitive diagnosis of many viruses, bacteria and intestinal protozoa, and are increasingly utilised as adjuncts for helminth identification. CONCLUSIONS: Diagnosis of the broad spectrum of intestinal pathogens is often cumbersome. There is a need for rapid diagnostic tests that are simple and affordable for resource-constrained settings, so that the management of patients suffering from persistent digestive disorders can be improved.
has issue date	2013-01-24(xsd:dateTime)
bibo:doi	10.1186/1471-2334-13-37
bibo:pmid	23347408
has license	cc-by
sha1sum (hex)	426d73371e7f29a3d046687525d416f68708f643
schema:url	https://doi.org/10.1186/1471-2334-13-37
resource representing a document's title	Persistent digestive disorders in the tropics: causative infectious pathogens and reference diagnostic tests
has PubMed Central identifier	PMC3579720
has PubMed identifier	23347408
schema:publication	BMC Infect Dis
resource representing a document's body	covid:426d73371e7f29a3d046687525d416f68708f643#body_text
is schema:about of	named entity 'tests' named entity 'digestive disorders' named entity 'tropics' named entity 'digestive' covid:arg/426d73371e7f29a3d046687525d416f68708f643 named entity 'DESCRIBED' named entity 'ACUTE' named entity 'OVERVIEW' named entity 'REVIEWED' named entity 'DIGESTIVE DISORDERS' named entity 'PROVIDING' named entity 'DISEASE' named entity 'REFERENCE' named entity 'SPECIFIC' named entity 'TREATMENT' named entity 'DIAGNOSTIC' named entity 'MOLECULAR' named entity 'PLAY' named entity 'RISE' named entity 'ROLES' named entity 'HELMINTHS' named entity 'LITERATURE' named entity 'DIAGNOSIS' named entity 'BUT' named entity 'UNCLEAR' named entity 'IMMUNOLOGICAL TESTS' named entity 'UNDERSTANDING' named entity 'TROPICS' named entity 'BURDEN' named entity '28I' named entity 'PATHOGEN' named entity 'CONSIDERABLE' named entity 'CULTURE TECHNIQUES' named entity 'DIARRHOEA' named entity 'GREATER' named entity 'BLOOD' named entity 'EXTENT OF' named entity 'REFERENCE' named entity 'SPECTRUM' named entity 'PERSISTENT' named entity 'CHRONIC ABDOMINAL PAIN' named entity 'TESTS' named entity 'IMPORTANT' named entity 'GASTROINTESTINAL INFECTIONS' named entity 'HIGHEST' named entity 'ACCOUNT' named entity 'STOOL' named entity 'INFECTIOUS' named entity 'INTESTINAL PROTOZOA' named entity 'TROPICS' named entity 'DIAGNOSTIC TESTS' named entity 'PATHOGENS' named entity 'EPIDEMIOLOGY' named entity 'MAJOR' named entity 'CONSIDERED' named entity 'ISSUES' named entity 'TO IDENTIFY' named entity 'SEARCHED' named entity 'PATHOGENS' named entity 'CAUSING' named entity 'DIAGNOSTIC ACCURACY'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software