About: Detection and characterization of respiratory viruses causing acute respiratory illness and asthma exacerbation in children during three different seasons (2011

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About: Detection and characterization of respiratory viruses causing acute respiratory illness and asthma exacerbation in children during three different seasons (2011–2014) in Mexico City Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Detection and characterization of respiratory viruses causing acute respiratory illness and asthma exacerbation in children during three different seasons (2011–2014) in Mexico City
Creator	Alejandre-Garcia, Alejandro Castillejos-Lopez, Manuel Hernandez, Andres Moreno-Valencia, Yazmin Perez-Padilla, Rogelio Coronel-Tellez, Rodrigo Romero-Espinoza, Jose Vazquez-Perez, Joel Hernandez-Hernandez, Victor Ormsby, Christopher De La Rosa-Zamboni, Daniela
source	Medline; PMC
abstract	BACKGROUND: Viral infections play a significant role in causing acute respiratory infections (ARIs) and exacerbations of chronic diseases. Acute respiratory infections are now the leading cause of mortality in children worldwide, especially in developing countries. Recently, human rhinovirus (HRV) infection has been emerged as an important cause of pneumonia and asthma exacerbation. OBJECTIVES: To determine the role of several viral agents principally, respiratory syncytial virus, and HRV in children with ARIs and their relationship with asthma exacerbation and pneumonia. METHODS: Between October 2011 and March 2014, 432 nasopharyngeal samples of children <15 years of age with ARI hospitalized at a referral hospital for respiratory diseases were tested for the presence of respiratory viruses using a multiplex RT-qPCR. Clinical, epidemiological, and demographic data were collected and associated with symptomatology and viral infections. RESULTS: Viral infections were detected in at least 59·7% of the enrolled patients, with HRV (26·6%) being the most frequently detected. HRV infections were associated with clinical features of asthma and difficulty in breathing such as wheezing (P = 0·0003), supraesternal (P = 0·046), and xiphoid retraction (P = 0·030). HRV subtype C (HRV-C) infections were associated with asthma (P = 0·02). CONCLUSIONS: Human rhinovirus was the virus most commonly detected in pediatric patients with ARI. There is also an association of HRV-C infection with asthma exacerbation, emphasizing the relevance of this virus in severe pediatric respiratory disease.
has issue date	2015-10-13(xsd:dateTime)
bibo:doi	10.1111/irv.12346
bibo:pmid	26289993
has license	cc-by
sha1sum (hex)	425be277181521bab21a8e64d54657dfdcac6bde
schema:url	https://doi.org/10.1111/irv.12346
resource representing a document's title	Detection and characterization of respiratory viruses causing acute respiratory illness and asthma exacerbation in children during three different seasons (2011–2014) in Mexico City
has PubMed Central identifier	PMC4605408
has PubMed identifier	26289993
schema:publication	Influenza Other Respir Viruses
resource representing a document's body	covid:425be277181521bab21a8e64d54657dfdcac6bde#body_text
is schema:about of	named entity 'asthma' named entity 'ACUTE RESPIRATORY ILLNESS' named entity 'CHILDREN' named entity 'DETECTION' named entity 'RESPIRATORY VIRUSES' named entity 'ASTHMA EXACERBATION' named entity 'CHARACTERIZATION' named entity 'DIFFERENT' named entity 'MEXICO CITY' named entity 'CAUSING' named entity 'SEASONS' named entity 'Human rhinovirus' named entity 'infection' named entity 'virus' named entity 'Vienna' named entity 'infection' named entity 'respiratory illness' named entity 'developing countries' named entity 'Acute respiratory infections' named entity 'SPSS' named entity 'wheezing' named entity 'influenza virus' named entity 'Armonk' named entity 'morbidity' named entity 'informed consent' named entity 'Roche' named entity 'RSV infection' named entity 'STATA' named entity 'Mexico City' named entity 'clinical significance' named entity 'HPIV' named entity 'Mexico' named entity 'chest roentgenogram' named entity 'shortness of breath' named entity 'HRV' named entity 'upper respiratory tract' named entity 'high-throughput' named entity 'respiratory symptoms' named entity 'comorbidities' named entity 'community-acquired pneumonia' named entity 'clinical symptoms' named entity 'asthma' named entity 'RSV infection' named entity 'HRV' named entity 'odds ratios' named entity 'CONACYT' named entity '95% CI' named entity 'HMPV' named entity 'wheezing' named entity 'infection' named entity 'respiratory infections' named entity 'coronavirus' named entity 'RSV' named entity 'viruses' named entity 'etiological' named entity 'wheezing' named entity 'nucleic acids' named entity 'ARIs' named entity 'asthma' named entity 'nasopharyngeal swabs' named entity 'ARI' named entity 'gastroesophageal reflux' named entity 'wheezing' named entity 'asthma' named entity 'Mexico City' named entity 'HRV' named entity '95% CI' named entity 'comorbidities' named entity 'pneumonia' named entity 'hypoxemia' named entity 'pathogens'

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