About: Immune function of an angiotensin-converting enzyme against Rice stripe virus infection in a vector insect

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About: Immune function of an angiotensin-converting enzyme against Rice stripe virus infection in a vector insect Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Immune function of an angiotensin-converting enzyme against Rice stripe virus infection in a vector insect
Creator	Li, Jing Wang, Wei Wang, Xue Cui, Feng Qiao, Luqin Zhang, Wenzhong
Source	Elsevier; Medline; PMC
abstract	Abstract Angiotensin-converting enzyme (ACE) plays diverse roles in the animal kingdom. However, whether ACE plays an immune function against viral infection in vector insects is unclear. In this study, an ACE gene (LsACE) from the small brown planthopper was found to respond to Rice stripe virus (RSV) infection. The enzymatic activities of LsACE were characterized at different pH and temperature. Twenty planthopper proteins were found to interact with LsACE. RSV infection significantly upregulated LsACE expression in the testicle and fat body. When the expression of LsACE in viruliferous planthoppers was inhibited, the RNA level of the RSV SP gene was upregulated 2-fold in planthoppers, and all RSV genes showed higher RNA levels in the rice plants consumed by these planthoppers, leading to a higher viral infection rate and disease rating index. These results indicate that LsACE plays a role in the immune response against RSV transmission by planthoppers.
has issue date	2019-07-31(xsd:dateTime)
bibo:doi	10.1016/j.virol.2019.05.007
bibo:pmid	31247402
has license	els-covid
sha1sum (hex)	42085d63b0fbfc03c555626cadd11d55774c5c64
schema:url	https://doi.org/10.1016/j.virol.2019.05.007
resource representing a document's title	Immune function of an angiotensin-converting enzyme against Rice stripe virus infection in a vector insect
has PubMed Central identifier	PMC7127076
has PubMed identifier	31247402
schema:publication	Virology
resource representing a document's body	covid:42085d63b0fbfc03c555626cadd11d55774c5c64#body_text
is schema:about of	named entity 'RNA' named entity 'function' named entity 'VIRUS INFECTION' named entity 'ANGIOTENSIN-CONVERTING ENZYME' named entity 'ANIMAL KINGDOM' named entity 'INFECTION RATE' named entity 'ACE GENE' named entity 'DIFFERENT' named entity 'LEVELS' named entity 'RICE' named entity 'RSV INFECTION' named entity 'PLANTS' named entity 'CHARACTERIZED' named entity 'FAT BODY' named entity 'DISEASE RATING' named entity 'PLAYS' named entity 'ACTIVITIES' named entity 'RESULTS' named entity 'SMALL BROWN PLANTHOPPER' named entity 'INFECTION' named entity 'TO INTERACT WITH' named entity 'TRANSMISSION' named entity 'IMMUNE RESPONSE' named entity 'TESTICLE' named entity 'RNA' named entity 'HIGHER' named entity 'INDEX' named entity 'ROLES' named entity 'TWENTY' named entity 'PROTEINS' named entity 'GENES' named entity 'INSECTS' named entity 'LEADING' named entity 'VIRAL INFECTION' named entity 'FOLD' named entity 'TEMPERATURE' named entity 'UPREGULATED' named entity 'INSECT' named entity 'RICE STRIPE VIRUS' named entity 'IMMUNE FUNCTION' named entity 'THESE' named entity 'UNCLEAR' named entity 'TO RESPOND' named entity 'RICE STRIPE VIRUS' named entity 'ENZYMATIC' named entity 'STUDY' named entity 'RESPOND TO' named entity 'ACE' named entity 'GENE' named entity 'FOUND' named entity 'IMMUNE FUNCTION' named entity 'EXPRESSION' named entity 'ROLE' named entity 'LEVEL' named entity 'DIVERSE' named entity 'VECTOR' named entity 'ANGIOTENSIN-CONVERTING ENZYME' named entity 'PLANTHOPPER' named entity 'RSV' named entity 'INHIBITED' named entity 'VECTOR' covid:arg/42085d63b0fbfc03c555626cadd11d55774c5c64 named entity 'planthoppers' named entity 'RSV' named entity 'ovary' named entity 'beta-tubulin' named entity 'clones' named entity 'Clontech' named entity 'plant virus' named entity 'SPSS' named entity 'respond' named entity 'viral infection' named entity 'infection' named entity 'RNA' named entity 'immune response' named entity 'infection'

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