About: Is there a clinical difference between influenza A and B virus infections in hospitalized patients?: Results after routine polymerase chain reaction point-of-care testing in the emergency room from 2017/2018

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About: Is there a clinical difference between influenza A and B virus infections in hospitalized patients?: Results after routine polymerase chain reaction point-of-care testing in the emergency room from 2017/2018 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Is there a clinical difference between influenza A and B virus infections in hospitalized patients?: Results after routine polymerase chain reaction point-of-care testing in the emergency room from 2017/2018
Creator	Laferl, Hermann Laferl, H Daller, Simon Kaczmarek, Caroline Karolyi, Mario Niculescu, Iulia Pawelka, Erich Schrader, Birte Stütz, Christian Wenisch, Christoph Zoufaly, Alexander Karolyi, M Pawelka, E Wenisch, · Zoufaly, · Daller, S Kaczmarek, · Niculescu, · Schrader, · Stütz, ·
Source	PMC
abstract	PURPOSE: The clinical presentation, complications and mortality in molecularly confirmed influenza A and B infections were analyzed. METHODS: This retrospective observational single-centre study included all influenza positive patients older than 18 years who were hospitalized and treated at the flu isolation ward during 2017/2018. The diagnosis was based on point-of-care tests with the Alere(TM). RESULTS: Of the 396 patients tested positive for influenza, 24.2% had influenza A and 75.8% influenza B. Influenza A patients were younger (median age 67.5 years vs. 77 years, p < 0.001), were more often smokers (27.7% vs. 16.8%, p = 0.021), had chronic pulmonary diseases more frequently (39.6% vs. 26.3%, p = 0.013), presented with a higher body temperature (38.6 °C vs. 38.3 °C, p = 0.004), leucocyte count (8 G/L vs. 6.8 G/L, p = 0.002), C‑reactive protein (CRP) level (41 mg/l vs. 23 mg/l, p < 0.001) and had dyspnea more often (41.7% vs. 28%, p = 0.012). Influenza B patients had an underlying chronic kidney disease in 37% vs. 18.8% (p < 0.001) and presented with vomiting on admission more frequently (21.7% vs. 11.5%, p = 0.027). Influenza A patients were admitted for 8 days vs. 7 days (p = 0.023). There were no differences in the rate of complications; however, 22 (5.6%) patients died during the hospital stay. The in-hospital mortality was higher in influenza A patients (8.3% vs 4.7%, p = 0.172). CONCLUSION: Some differences were found between influenza A and B virus infections but symptoms were overlapping, which necessitates polymerase chain reaction point-of-care testing for accurate diagnosis. Influenza A was a more severe disease than influenza B during the period 2017/2018.
has issue date	2019-06-18(xsd:dateTime)
bibo:doi	10.1007/s00508-019-1519-0
bibo:pmid	31214922
has license	no-cc
sha1sum (hex)	4133adb497f900e4ea0651dcffebe44675a84b48
schema:url	https://doi.org/10.1007/s00508-019-1519-0
resource representing a document's title	Is there a clinical difference between influenza A and B virus infections in hospitalized patients?: Results after routine polymerase chain reaction point-of-care testing in the emergency room from 2017/2018
has PubMed Central identifier	PMC7101895
has PubMed identifier	31214922
schema:publication	Wien Klin Wochenschr
resource representing a document's body	covid:4133adb497f900e4ea0651dcffebe44675a84b48#body_text
is schema:about of	named entity 'observational' named entity 'INCLUDED' named entity 'STUDY' named entity 'WARD' named entity 'INFLUENZA' named entity 'CONFIRMED' named entity 'BASED' named entity 'POINT-OF-CARE' covid:arg/4133adb497f900e4ea0651dcffebe44675a84b48 named entity 'molecularly' named entity 'patients' named entity 'clinical' named entity 'treated' named entity 'retrospective' named entity 'mortality' named entity 'infections' named entity 'influenza A' named entity 'polymerase' named entity 'Alere' named entity 'point-of-care tests' named entity 'emergency room' named entity 'virulence' named entity 'influenza infection' named entity 'nucleic acid amplification' named entity 'sore throat' named entity 'high-risk' named entity 'immunoassays' named entity 'influenza' named entity 'PCR' named entity 'questionnaire' named entity 'X-ray' named entity 'vomiting' named entity 'influenza' named entity 'MS Excel' named entity 'chronic diseases' named entity 'influenza' named entity 'POCT' named entity 'vomiting' named entity 'alanine aminotransferase' named entity 'respiratory failure' named entity 'Austria' named entity 'Antibiotics' named entity 'influenza' named entity 'ALAT' named entity 'influenza' named entity 'CRP' named entity 'diabetes' named entity 'diabetes' named entity 'oseltamivir' named entity 'epidemics' named entity 'emergency departments' named entity 'Influenza' named entity 'LDH' named entity 'influenza virus' named entity 'in-patient care' named entity 'oxygen saturation' named entity 'study population' named entity 'RDT' named entity 'chronic pulmonary disease' named entity 'fever' named entity 'vaccination' named entity 'influenza'

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