About: Filovirus Entry

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Filovirus Entry
Creator	Simmons, Graham
Source	Medline; PMC
abstract	A number of advances in recent years have significantly furthered our understanding of filovirus attachment and cellular tropism. For example, several cell-surface molecules have been identified as attachment factors with the potential to facilitate the in vivo targeting of particular cell types such as macrophages and hepatic cells. Furthermore, our knowledge of internalization and subsequent events during filovirus entry has also been widened, adding new variations to the paradigms for viral entry established for HIV and influenza. In particular, host cell factors such as endosomal proteases and the intracellular receptor Niemann-Pick C1 are now known to play a vital role in activating the membrane fusion potential of filovirus glycoproteins.
has issue date	2013-07-10(xsd:dateTime)
bibo:doi	10.1007/978-1-4614-7651-1_5
bibo:pmid	23884587
has license	no-cc
sha1sum (hex)	40c6bb24155330f849cbdb434a23ccc0cd43b7be
schema:url	https://doi.org/10.1007/978-1-4614-7651-1_5
resource representing a document's title	Filovirus Entry
has PubMed Central identifier	PMC7114988
has PubMed identifier	23884587
schema:publication	Viral Entry into Host Cells
resource representing a document's body	covid:40c6bb24155330f849cbdb434a23ccc0cd43b7be#body_text
is schema:about of	named entity 'FILOVIRUS' named entity 'ENTRY' named entity 'EVENTS' named entity 'PLAY' named entity 'MACROPHAGES' named entity 'POTENTIAL' named entity 'PARADIGMS' named entity 'CELL' named entity 'FILOVIRUS' named entity 'INTRACELLULAR' named entity 'OUR' named entity 'KNOWLEDGE' named entity 'ESTABLISHED' named entity 'ATTACHMENT' named entity 'CELLULAR TROPISM' named entity 'CELL TYPES' named entity 'NEW' named entity 'UNDERSTANDING' named entity 'IN VIVO' named entity 'MEMBRANE FUSION' named entity 'PROTEASES' named entity 'TARGETING' named entity 'MOLECULES' named entity 'VARIATIONS' named entity 'VIRAL ENTRY' named entity 'INTERNALIZATION' named entity 'ENTRY' named entity 'PICK' named entity 'RECEPTOR' named entity 'PARTICULAR' named entity 'VITAL' named entity 'EXAMPLE' named entity 'WIDENED' named entity 'KNOWN' named entity 'IDENTIFIED' named entity 'HEPATIC CELLS' named entity 'NUMBER OF' named entity 'ACTIVATING' named entity 'HIV' named entity 'SURFACE' named entity 'YEARS' named entity 'RECENT' named entity 'ADDING' named entity 'ROLE' named entity 'HAVE' named entity 'GLYCOPROTEINS' named entity 'HOST CELL' named entity 'INFLUENZA' named entity 'SUBSEQUENT' named entity 'virus' named entity 'CD209' named entity 'immune responses' named entity 'Calcium' named entity 'CD209' named entity 'infection' named entity 'infection' named entity 'serum' named entity 'virus' named entity 'conformational change' named entity 'carbohydrate' named entity 'galactose' named entity 'antibodies' named entity 'expression levels' named entity 'CTSB' named entity 'mannose' named entity 'plasma membrane' named entity 'competent cell' named entity 'virus' named entity 'ASGP' named entity 'EBOV' named entity 'EBOV' named entity 'galactose' named entity 'viruses' named entity 'CD209' named entity 'cDNA' named entity 'TAFV' named entity 'EBOV' named entity 'filoviruses' named entity 'dendritic cells' named entity 'lymph nodes' named entity 'infection'

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