About: Clinical Features of Human Metapneumovirus Pneumonia in Non-Immunocompromised Patients: An Investigation of Three Long-Term Care Facility Outbreaks

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About: Clinical Features of Human Metapneumovirus Pneumonia in Non-Immunocompromised Patients: An Investigation of Three Long-Term Care Facility Outbreaks Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Clinical Features of Human Metapneumovirus Pneumonia in Non-Immunocompromised Patients: An Investigation of Three Long-Term Care Facility Outbreaks
Creator	Nishimura, Hidekazu Okamoto, Michiko Fujita, Jiro Kinjo, Takeshi Higa, Futoshi Nabeya, Daijiro Haranaga, Shusaku Parrott, Gretchen Tateyama, Masao Uehara, Ayako Karimata, Yosuke Kishaba, Tomoo Miyagawa, Keiko Otani, Kanako
Source	Medline; PMC
abstract	BACKGROUND: Several studies have reported outbreaks due to human metapneumovirus (hMPV) in long-term care facilities (LTCF) for the elderly. However, most of these reports are epidemiological studies and do not investigate the clinical features of hMPV pneumonia. METHODS: Three independent outbreaks of hMPV occurred at separate LTCF for intellectually challenged and elderly residents. A retrospective evaluation of hMPV pneumonia and its clinical and radiological features was conducted using available medical records and data. RESULTS: In 105 hMPV infections, 49% of patients developed pneumonia. The median age of pneumonia cases was significantly higher than non-pneumonia cases (P < .001). Clinical manifestations of hMPV pneumonia included high fever, wheezing in 43%, and respiratory failure in 31% of patients. An elevated number of white blood cells as well as increased levels of C-reactive protein, creatine phosphokinase, and both aspartate and alanine transaminases was also observed among pneumonia cases. Evaluation of chest imaging revealed proximal bronchial wall thickenings radiating outward from the hilum in most patients. CONCLUSIONS: The aforementioned characteristics should be considered as representative of hMPV pneumonia. Patients presenting with these features should have laboratory testing performed for prompt diagnosis.
has issue date	2018-09-15(xsd:dateTime)
bibo:doi	10.1093/infdis/jiy261
bibo:pmid	29733351
has license	no-cc
sha1sum (hex)	3f70c62951796b62a7ce61fe4650939a5840c2ed
schema:url	https://doi.org/10.1093/infdis/jiy261
resource representing a document's title	Clinical Features of Human Metapneumovirus Pneumonia in Non-Immunocompromised Patients: An Investigation of Three Long-Term Care Facility Outbreaks
has PubMed Central identifier	PMC7107412
has PubMed identifier	29733351
schema:publication	J Infect Dis
resource representing a document's body	covid:3f70c62951796b62a7ce61fe4650939a5840c2ed#body_text
is schema:about of	named entity 'INFECTIOUS DISEASES' named entity 'The Journal' named entity 'MOST OF' named entity 'STUDIES' named entity 'HAVE' named entity 'LONG-TERM CARE' named entity 'BACKGROUND' named entity 'INVESTIGATE' named entity 'INVESTIGATION' named entity 'ELDERLY' named entity 'HUMAN METAPNEUMOVIRUS PNEUMONIA' named entity 'OUTBREAKS' named entity 'LONG-TERM CARE FACILITY' named entity 'CLINICAL FEATURES' named entity 'NON-' named entity 'IMMUNOCOMPROMISED PATIENTS' named entity 'JOURNAL ' named entity 'OUTBREAKS' named entity 'REPORTS' named entity 'THESE' named entity 'DO NOT' named entity 'EPIDEMIOLOGICAL STUDIES' named entity 'FACILITIES' named entity 'HUMAN METAPNEUMOVIRUS' named entity 'PNEUMONIA' named entity 'CLINICAL FEATURES' named entity 'DUE TO' named entity 'REPORTED' covid:arg/3f70c62951796b62a7ce61fe4650939a5840c2ed named entity 'features' named entity 'Outbreaks' named entity 'human metapneumovirus' named entity 'long-term care facilities' named entity 'Clinical Features' named entity 'Immunocompromised Patients' named entity 'However' named entity 'oxygen therapy' named entity 'hMPV' named entity 'pneumonia' named entity 'chest x-ray' named entity 'CRP' named entity 'hMPV' named entity 'LTCF' named entity 'body temperature' named entity 'antigen' named entity 'chest x-ray' named entity 'RAT' named entity 'imaging tests' named entity 'self-limiting' named entity 'RAT' named entity 'pneumonia' named entity 'subtropical region' named entity 'pneumonia' named entity 'WBC' named entity 'pathogens' named entity 'PCR testing' named entity 'rhabdomyolysis' named entity 'antibody' named entity 'PCR' named entity 'Seoul' named entity 'Francisella tularensis' named entity 'pneumonia' named entity 'hMPV' named entity 'differential diagnosis' named entity 'older adults' named entity 'clinical features' named entity 'Billerica' named entity 'AST'

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