About: Infectious diseases of the upper respiratory tract: implications for toxicology studies.

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Infectious diseases of the upper respiratory tract: implications for toxicology studies.
Creator	Everitt, Jeffrey Richtert, Conrad
Source	Medline; PMC
abstract	The consequences of adventitious infectious agents upon the interpretation of toxicology studies performed in rats and mice are incompletely understood. Several prevalent murine pathogens cause alterations of the respiratory system that can confuse the assessment of chemically induced airway injury. In some instances the pathogenesis of infection with these agents has been relatively well studied in the lower respiratory tract. However, there are few well-controlled studies that have examined the upper respiratory region, which result in interpretive problems for toxicologic pathologists. The conduct and interpretation of both short-term and chronic rodent bioassays can be compromised by both the clinical and subclinical manifestations of infectious diseases. This paper reviews several important infectious diseases of the upper airway of rats and mice and discusses the potential influence of these conditions on the results of toxicology studies.
has issue date	1990-04-01(xsd:dateTime)
bibo:pmid	2200664
has license	no-cc
sha1sum (hex)	3b5579588b12f1f4bd5e6c1eea4c8ba0258a4f57
resource representing a document's title	Infectious diseases of the upper respiratory tract: implications for toxicology studies.
has PubMed Central identifier	PMC1568352
has PubMed identifier	2200664
schema:publication	Environ Health Perspect
resource representing a document's body	covid:3b5579588b12f1f4bd5e6c1eea4c8ba0258a4f57#body_text
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