About: In vivo gene delivery mediated by non-viral vectors for cancer therapy

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	In vivo gene delivery mediated by non-viral vectors for cancer therapy
Creator	Pardakhty, Abbas Afshar, Ghasemipour Ashrafizadeh, Milad Dehshahri, Ali Edu, Alizarrabi@sabanciuniv Ghasemipour Afshar, Elham Khorsandi, Danial Madamsetty, Vijay Makvandi, Pooyan Mohammadinejad, Reza Tavakol, Shima Zahmatkeshan, Masoumeh Zarrabi, Ali
source	Elsevier; Medline; PMC
abstract	Gene therapy by expression constructs or down-regulation of certain genes has shown great potential for the treatment of various diseases. The wide clinical application of nucleic acid materials dependents on the development of biocompatible gene carriers. There are enormous various compounds widely investigated to be used as non-viral gene carriers including lipids, polymers, carbon materials, and inorganic structures. In this review, we will discuss the recent discoveries on non-viral gene delivery systems. We will also highlight the in vivo gene delivery mediated by non-viral vectors to treat cancer in different tissue and organs including brain, breast, lung, liver, stomach, and prostate. Finally, we will delineate the state-of-the-art and promising perspective of in vivo gene editing using non-viral nano-vectors.
has issue date	2020-07-04(xsd:dateTime)
bibo:doi	10.1016/j.jconrel.2020.06.038
bibo:pmid	32634464
has license	no-cc
sha1sum (hex)	395b1f11c6bad60311a05bf827a331c3648870d5
schema:url	https://doi.org/10.1016/j.jconrel.2020.06.038
resource representing a document's title	In vivo gene delivery mediated by non-viral vectors for cancer therapy
has PubMed Central identifier	PMC7334939
has PubMed identifier	32634464
schema:publication	J Control Release
resource representing a document's body	covid:395b1f11c6bad60311a05bf827a331c3648870d5#body_text
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