About: Association between NO(2)cumulative exposure and influenza prevalence in mountainous regions: A case study from Southwest China

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Association between NO(2)cumulative exposure and influenza prevalence in mountainous regions: A case study from Southwest China
Creator	Liu, Rui Zeng, Wen Qiu, Yang Shu, Chang Yang, Y Zhao, Han Liu, R Yan, W Zhao, H Zeng, W Shu, F Yan, Wei Yang, Fumo Zhan, C Zhan, Yu
Source	Elsevier; PMC
abstract	While accumulating evidence shows that air pollution exposure is an important risk factor to influenza prevalence, their association has been inadequately investigated in mountainous regions with dense populations and high humidity. We aim to estimate the association and exposure-outcome effects between exposure to nitrogen dioxide (NO(2)) and influenza prevalence in a mountainous region with a dense population and high humidity. We investigated 14,993 patients with confirmed influenza cases from January 2013 to December 2017 in Chongqing, a mountainous city in southwest China. We developed distributed lag non-linear models with quasi-Poisson link to take into account the lag and non-linear effects of NO(2) exposure on influenza prevalence. We estimated that the cumulative effect of a 10 μg/m(3) increase in NO(2) with seven-day lag (i.e., summing all the contributions up to seven days) corresponded to relative risk of 1.24 (95% CI: 1.17-1.31) in daily influenza prevalence. Comparing to annual mean of the World Health Organization air quality guidelines of 40 μg/m(3) for NO(2), we estimated that 14.01% (95% CI: 10.69-17.08%) of the influenza cases were attributable to excessive NO(2) exposure. Our results suggest that NO(2) exposure could worsen the risk of influenza infection in this mountainous city, filling the gap of relevant researches in densely populated and mountainous cities. Our findings provide evidence for developing influenza surveillance and early warning systems.
has issue date	2020-07-12(xsd:dateTime)
bibo:doi	10.1016/j.envres.2020.109926
has license	no-cc
sha1sum (hex)	388d3cef1836ec4d251ab3ffbdc4cbcc978991b3
schema:url	https://doi.org/10.1016/j.envres.2020.109926
resource representing a document's title	Association between NO(2)cumulative exposure and influenza prevalence in mountainous regions: A case study from Southwest China
has PubMed Central identifier	PMC7354378
schema:publication	Environ Res
resource representing a document's body	covid:388d3cef1836ec4d251ab3ffbdc4cbcc978991b3#body_text
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