About: A novel three-dimensional aerogel biochip for molecular recognition of nucleotide acids

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About: A novel three-dimensional aerogel biochip for molecular recognition of nucleotide acids Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A novel three-dimensional aerogel biochip for molecular recognition of nucleotide acids
Creator	Su, Hung-Ju Wu, Jui-Chuang Chen, Yun-Chu Yang, Den-Kai Chen-Yang, Yui Li, Yen
Source	Elsevier; Medline; PMC
abstract	Mesoporous aerogel was produced under regular atmospheric conditions using the sol–gel polymerization of tetraethyl orthosilicate with an ionic liquid as both solvent and active agent. This was then used to build a three-dimensional structure to recognize nucleotide acids. Fourier transformation infrared spectroscopy, scanning electron microscopy, (29)Si solid-state nuclear magnetic resonance, and Brunauer–Emmett–Teller instruments were used to characterize this 3D aerogel, demonstrating that it had high porosity and large internal networking surface area that could capture nucleotide acids. The functionality of molecular recognition on nucleotide acids was demonstrated by immobilizing an oligonucleotide to probe its DNA target and confirming the tagged fluorescent signals by confocal laser scanning microscopy. The results indicated that the as-prepared 3D bioaerogel was capable of providing a very large surface area to capture and recognize human gene ATP5O.
has issue date	2009-10-08(xsd:dateTime)
bibo:doi	10.1016/j.actbio.2009.10.001
bibo:pmid	19818421
has license	no-cc
sha1sum (hex)	37a4d82cdb3508b6434e6ea44a8518d92b8c5cc6
schema:url	https://doi.org/10.1016/j.actbio.2009.10.001
resource representing a document's title	A novel three-dimensional aerogel biochip for molecular recognition of nucleotide acids
has PubMed Central identifier	PMC7105051
has PubMed identifier	19818421
schema:publication	Acta Biomater
resource representing a document's body	covid:37a4d82cdb3508b6434e6ea44a8518d92b8c5cc6#body_text
is schema:about of	named entity 'porosity' named entity 'NOVEL' named entity 'SIGNALS' named entity 'CONFIRMING' named entity 'FLUORESCENT' named entity 'TELLER' named entity 'CAPTURE' named entity 'TO CHARACTERIZE' named entity 'ITS' named entity 'PROVIDING' named entity 'PREPARED' named entity 'OLIGONUCLEOTIDE' named entity 'BUILD' named entity 'IONIC LIQUID' named entity 'USING' named entity 'AGENT' named entity 'SURFACE AREA' named entity 'AEROGEL' named entity 'IMMOBILIZING' named entity 'TARGET' named entity 'REGULAR' named entity 'SOLVENT' named entity 'CAPABLE' named entity 'MOLECULAR RECOGNITION' named entity 'ATP5O' named entity 'STATE' named entity 'SOL-GEL' named entity 'SCANNING ELECTRON MICROSCOPY' named entity 'THREE-DIMENSIONAL' named entity 'AEROGEL' named entity 'STRUCTURE' named entity 'HUMAN GENE' covid:arg/37a4d82cdb3508b6434e6ea44a8518d92b8c5cc6 named entity 'RECOGNIZE' named entity 'ACTIVE' named entity 'ATMOSPHERIC CONDITIONS' named entity 'POROSITY' named entity 'FOURIER TRANSFORMATION' named entity 'INTERNAL' named entity 'RESULTS' named entity 'CONFOCAL LASER SCANNING MICROSCOPY' named entity 'NUCLEOTIDE' named entity 'THREE-DIMENSIONAL' named entity 'LARGE' named entity 'NETWORKING' named entity 'ACIDS' named entity 'MOLECULAR RECOGNITION' named entity 'BIOCHIP' named entity 'DEMONSTRATED' named entity 'INDICATED' named entity 'FUNCTIONALITY' named entity 'TAGGED' named entity 'USED' named entity 'MESOPOROUS' named entity 'NUCLEAR MAGNETIC RESONANCE' named entity 'POLYMERIZATION' named entity 'ACIDS' named entity 'TETRAETHYL ORTHOSILICATE' named entity 'SOLID' named entity 'EMMETT' named entity 'PROBE' named entity 'DNA' named entity 'INFRARED SPECTROSCOPY' named entity 'HIGH' named entity 'INSTRUMENTS' named entity 'NUCLEOTIDE' named entity 'VERY LARGE' named entity 'atmospheric' named entity 'scanning electron microscopy' named entity 'human' named entity 'solvent' named entity 'functionality' named entity 'polymerization' named entity 'acids' named entity 'Fourier transformation infrared spectroscopy' named entity 'gene'

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