About: The role of feline aminopeptidase N as a receptor for infectious bronchitis virus : Brief Review

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The role of feline aminopeptidase N as a receptor for infectious bronchitis virus : Brief Review
Creator	Miguel, B Pharr, G Wang, C
Source	Medline; PMC
abstract	Feline aminopeptidase N (fAPN) has been shown to serve as a receptor for feline, canine, porcine and human coronaviruses. Our objective was to determine if fAPN can serve as a receptor for infectious bronchitis virus (IBV). Feline kidney cells that express fAPN and hamster kidney fibroblasts that do not express fAPN were inoculated with IBV and monitored for replication by indirect fluorescent assay and confocal microscopy and in chicken embryonated eggs. The results showed that the feline cells were permissive to IBV but the hamster cells were not. The hamster cells became permissive to IBV after transfection with a fAPN cDNA suggesting that the feline APN molecule plays a role in IBV entry.
has issue date	2002-01-01(xsd:dateTime)
bibo:doi	10.1007/s00705-002-0888-1
bibo:pmid	12417943
has license	no-cc
sha1sum (hex)	374320be9c08609336a2ff4cb595adfe8bd4427d
schema:url	https://doi.org/10.1007/s00705-002-0888-1
resource representing a document's title	The role of feline aminopeptidase N as a receptor for infectious bronchitis virus : Brief Review
has PubMed Central identifier	PMC7086910
has PubMed identifier	12417943
schema:publication	Arch Virol
resource representing a document's body	covid:374320be9c08609336a2ff4cb595adfe8bd4427d#body_text
is schema:about of	named entity 'transfection' named entity 'cells' named entity 'human coronaviruses' named entity 'FELINE' named entity 'AMINOPEPTIDASE N' named entity 'HUMAN' named entity 'TRANSFECTION' named entity 'BUT' named entity 'CDNA' named entity 'DO NOT' named entity 'PLAYS' named entity 'REPLICATION' named entity 'MOLECULE' named entity 'EGGS' named entity 'RESULTS' named entity 'OBJECTIVE' named entity 'EXPRESS' named entity 'ROLE' named entity 'FLUORESCENT' named entity 'FIBROBLASTS' named entity 'MONITORED' named entity 'HAMSTER' named entity 'RECEPTOR' named entity 'INDIRECT' named entity 'CORONAVIRUSES' named entity 'SERVE' named entity 'CANINE' named entity 'AMINOPEPTIDASE N' named entity 'ASSAY' named entity 'INFECTIOUS BRONCHITIS VIRUS' named entity 'ROLE' named entity 'BRIEF' named entity 'RECEPTOR' named entity 'APN' named entity 'CELLS' named entity 'TO SERVE AS' named entity 'KIDNEY' named entity 'CONFOCAL MICROSCOPY' named entity 'DETERMINE' named entity 'REVIEW' named entity 'CHICKEN' named entity 'ENTRY' named entity 'OUR' named entity 'INFECTIOUS BRONCHITIS VIRUS' named entity 'PORCINE' named entity 'FELINE' covid:arg/374320be9c08609336a2ff4cb595adfe8bd4427d named entity 'determine' named entity 'virus' named entity 'confocal microscopy' named entity 'eggs' named entity 'serve' named entity 'serve' named entity 'embryonated' named entity 'indirect' named entity 'membrane bound' named entity 'FEK' named entity 'infection' named entity 'transfected' named entity 'canine' named entity 'receptor' named entity 'inoculated' named entity 'porcine' named entity 'Brief' named entity 'virus' named entity 'aminopeptidase N' named entity 'IBV' named entity 'transfection' named entity 'kidney cells' named entity 'infectious bronchitis virus' named entity 'cDNA' named entity 'fluorescent' named entity 'Manassas' named entity 'Newark' named entity 'embryo' named entity 'viruses' named entity 'coinfected' named entity 'supernatants' named entity '229E'

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