About: Dilated cardiomyopathy

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Dilated cardiomyopathy Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Dilated cardiomyopathy
Creator	Liu, Peter Schultheiss, Heinz-Peter Caforio, Alida Escher, Felicitas Fairweather, Delisa Hershberger, Ray Lipshultz, Steven Matsumori, Akira Mazzanti, Andrea Mcmurray, John Priori, Silvia
Source	PMC
abstract	Dilated cardiomyopathy (DCM) is a clinical diagnosis characterized by left ventricular or biventricular dilation and impaired contraction that is not explained by abnormal loading conditions (for example, hypertension and valvular heart disease) or coronary artery disease. Mutations in several genes can cause DCM, including genes encoding structural components of the sarcomere and desmosome. Nongenetic forms of DCM can result from different aetiologies, including inflammation of the myocardium due to an infection (mostly viral); exposure to drugs, toxins or allergens; and systemic endocrine or autoimmune diseases. The heterogeneous aetiology and clinical presentation of DCM make a correct and timely diagnosis challenging. Echocardiography and other imaging techniques are required to assess ventricular dysfunction and adverse myocardial remodelling, and immunological and histological analyses of an endomyocardial biopsy sample are indicated when inflammation or infection is suspected. As DCM eventually leads to impaired contractility, standard approaches to prevent or treat heart failure are the first-line treatment for patients with DCM. Cardiac resynchronization therapy and implantable cardioverter–defibrillators may be required to prevent life-threatening arrhythmias. In addition, identifying the probable cause of DCM helps tailor specific therapies to improve prognosis. An improved aetiology-driven personalized approach to clinical care will benefit patients with DCM, as will new diagnostic tools, such as serum biomarkers, that enable early diagnosis and treatment.
has issue date	2019-05-09(xsd:dateTime)
bibo:doi	10.1038/s41572-019-0084-1
bibo:pmid	31073128
has license	no-cc
sha1sum (hex)	36e6327b43958d4e08726a60e41dbe5c6394b3b3
schema:url	https://doi.org/10.1038/s41572-019-0084-1
resource representing a document's title	Dilated cardiomyopathy
has PubMed Central identifier	PMC7096917
has PubMed identifier	31073128
schema:publication	Nat Rev Dis Primers
resource representing a document's body	covid:36e6327b43958d4e08726a60e41dbe5c6394b3b3#body_text
is schema:about of	named entity 'CLINICAL DIAGNOSIS' named entity 'CORRECT' named entity 'COM' named entity 'PATIENTS' named entity 'BIOPSY SAMPLE' named entity 'INFECTION' named entity 'DISEASE' named entity 'TO PREVENT' named entity 'CARDIAC RESYNCHRONIZATION THERAPY' named entity 'ABNORMAL' named entity 'INFLAMMATION OR INFECTION' named entity 'DIAGNOSIS' named entity 'TAILOR' named entity 'AUTOIMMUNE DISEASES' named entity 'NEW' named entity 'SUSPECTED' named entity 'CITATION' named entity 'TOXINS' named entity 'ENCODING' named entity 'LOADING' named entity 'INCLUDING' named entity 'MYOCARDIUM' named entity 'INDICATED' named entity 'VIRAL' named entity 'EXPOSURE TO' named entity 'RESULT' named entity 'MYOCARDIAL' named entity 'DCM' named entity 'MAKE' named entity 'SARCOMERE' named entity 'IDENTIFYING' named entity 'INFLAMMATION' named entity 'SPECIFIC' named entity 'ARTICLE' named entity 'BENEFIT' named entity 'HETEROGENEOUS' named entity 'MAY BE' named entity 'MUTATIONS' named entity 'LEADS' named entity 'ASSESS' named entity 'REQUIRED' named entity 'CONDITIONS' named entity 'CONTRACTION' named entity 'FORMS' named entity 'LEFT' named entity 'IMAGING TECHNIQUES' named entity 'STRUCTURAL' named entity 'TOOLS' named entity 'CONTRACTILITY' named entity 'DILATED CARDIOMYOPATHY' named entity 'TREAT' named entity 'PROGNOSIS' named entity 'ARRHYTHMIAS' named entity 'VENTRICULAR' named entity 'DRUGS' named entity 'HEART FAILURE' named entity 'PRIMERS' named entity 'HISTOLOGICAL' named entity 'PERSONALIZED' named entity 'COMPONENTS' named entity 'DRIVEN' named entity 'TREATMENT' named entity 'HELPS' named entity 'TIMELY' named entity 'ADDITION' named entity 'DESMOSOME' named entity 'PROBABLE' named entity 'CHARACTERIZED' named entity 'SYSTEMIC' named entity 'APPROACH' named entity 'CLINICAL CARE'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software