About: Herpes zoster encephalitis presenting as multiple cerebral hemorrhages

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About: Herpes zoster encephalitis presenting as multiple cerebral hemorrhages – a rare presentation: a case report Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Herpes zoster encephalitis presenting as multiple cerebral hemorrhages – a rare presentation: a case report
Creator	Jajoo, Ulhas Khiangte, Benjamine Saxena, Amrish Tiewsoh, Iadarilang
Source	PMC
abstract	INTRODUCTION: An infection by herpes zoster virus is a common and important cause of encephalitis. Herpes zoster virus encephalitis if not treated promptly can result in significant morbidity and mortality. The diagnosis of herpes zoster virus encephalitis is based on clinical history, examination, neuroradiological imaging (magnetic resonance imaging and/or computed tomography scan), cerebrospinal fluid analysis and identification of the pathogen in cerebrospinal fluid by polymerase chain reaction amplification and/or anti-herpes zoster virus immunoglobulin G antibody in cerebrospinal fluid. Although ischemic intracerebral infarcts in patients with herpes zoster virus encephalitis or vasculopathy are reported in the literature, multiple intracerebral hemorrhages as a complication of herpes zoster virus encephalitis in an immunocompetent individual are extremely rare. CASE PRESENTATION: A 40-year-old Indian man presented with an acute history of four episodes of seizures, fever, headache, drowsiness, focal neurological deficits and vesicular eruptions over the abdomen in a typical dermatomal distribution. His head computed tomography scan revealed multiple cerebral hemorrhages. Investigations (positive ratio between the cerebrospinal fluid/serum quotients for anti-herpes zoster virus immunoglobulin G and total immunoglobulin G antibodies) established its infective origin due to herpes zoster virus. He developed bilateral pneumonia during the hospital course. He had an excellent recovery following a 2 weeks’ course of intravenous acyclovir. CONCLUSION: Herpes zoster virus encephalitis or vasculopathy is a rare cause of multiple intracerebral hemorrhages and must be considered in the differential diagnosis of patients presenting with an acute history of fever, altered consciousness, and focal neurologic deficits with history of a typical herpetic rash. Its prompt recognition and treatment could alter the course of illness.
has issue date	2013-06-18(xsd:dateTime)
bibo:doi	10.1186/1752-1947-7-155
bibo:pmid	23777620
has license	cc-by
sha1sum (hex)	36de0a2603f81b3678e4a3d0f10e1d1564dda5a1
schema:url	https://doi.org/10.1186/1752-1947-7-155
resource representing a document's title	Herpes zoster encephalitis presenting as multiple cerebral hemorrhages – a rare presentation: a case report
has PubMed Central identifier	PMC3693903
has PubMed identifier	23777620
schema:publication	J Med Case Rep
resource representing a document's body	covid:36de0a2603f81b3678e4a3d0f10e1d1564dda5a1#body_text
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