About: Clinical Trials and Tribulations in the COVID-19 Era

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Clinical Trials and Tribulations in the COVID-19 Era
Creator	Belmont, Ma Fnp-Bc, Forester, Brent Harper, David Hospital, Mclean Arnold, Steven Fnp-Bc, Jessica Gerber, Jessica Gerber, M Geriatric Psychiatry, B Harvard, May, Rose Mcmanus, Alison Owoyemi, Praise Patrick, Regan Program, Research Schwab, Nadine Scott, Marc Weinberg, Marc
Source	Elsevier; Medline; PMC
abstract	Advances in treating and preventing Alzheimer's disease and other neurocognitive disorders of aging arise from rigorous preclinical and clinical research, with randomized controlled treatment trials as the last and definitive test. The COVID-19 pandemic has greatly disrupted ongoing interventional studies and researchers are scrambling to find ways to safely continue this critical work amidst rapidly shifting guidelines from sponsors, institutions, and state and federal guidelines. Here we describe novel approaches and work-flow adaptations to study visits, drug delivery and interim and endpoint safety and outcomes assessments to avoid sacrificing years of preparation and substantial financial investments, to work in the best interest of participants and their caregivers, and to continue on the path towards discovering disease-modifying treatments for the millions of individuals impacted by major neurocognitive disorders.
has issue date	2020-05-19(xsd:dateTime)
bibo:doi	10.1016/j.jagp.2020.05.016
bibo:pmid	32507686
has license	no-cc
sha1sum (hex)	36b12099afef86297fbef332ea97301e91da9d5d
schema:url	https://doi.org/10.1016/j.jagp.2020.05.016
resource representing a document's title	Clinical Trials and Tribulations in the COVID-19 Era
has PubMed Central identifier	PMC7236727
has PubMed identifier	32507686
schema:publication	Am J Geriatr Psychiatry
resource representing a document's body	covid:36b12099afef86297fbef332ea97301e91da9d5d#body_text
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