About: Pediatric Airway Stent Designed to Facilitate Mucus Transport and Atraumatic Removal

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About: Pediatric Airway Stent Designed to Facilitate Mucus Transport and Atraumatic Removal Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Pediatric Airway Stent Designed to Facilitate Mucus Transport and Atraumatic Removal
Creator	Dupont, Pierre Ha, Junhyoung Kaza, Aditya Mondal, Abhijit Zhao, Zhanyue
Source	PMC
abstract	Objective: The goal was to develop a pediatric airway stent for treating tracheobronchomalacia that could be used as an alternative to positive pressure ventilation. The design goals were for the stent to allow mucus flow and to resist migration inside the airways, while also enabling easy insertion and removal. Methods: A helical stent design, together with insertion and removal tools, is presented. A mechanics model of stent compression is derived to assist in selecting stent design parameters (pitch and wire diameter) that provide the desired amount of tracheal support, while introducing the minimal amount of foreign material into the airway. Worst-case airway area reduction with stent support is investigated experimentally using a pressurized tracheal phantom matched to porcine tracheal tissue properties. The stent design is then evaluated in a porcine in vivo experiment. Results: Phantom testing validated the mechanics model of stent compression. In vivo testing demonstrated that the stent was well tolerated by the animal. Since the helical design covers only a small portion of the epithelium, mucus transport through the stented region was minimally impeded. Furthermore, the screw-like stent resisted migration, while also providing for atraumatic removal through the use of an unscrewing motion during removal. Conclusion: The proposed stent design and tools represent a promising approach to prevent airway collapse in children with tracheobronchomalacia. Significance: The proposed technology overcomes the limitations of existing airway stents and may provide an alternative to maintaining children on a ventilator.
has issue date	2019-04-11(xsd:dateTime)
bibo:doi	10.1109/tbme.2019.2910551
bibo:pmid	30990171
has license	cc-by
sha1sum (hex)	367fda3ef9ea317d3d0d5effbeba152f054cd4bd
schema:url	https://doi.org/10.1109/tbme.2019.2910551
resource representing a document's title	Pediatric Airway Stent Designed to Facilitate Mucus Transport and Atraumatic Removal
has PubMed Central identifier	PMC6947666
has PubMed identifier	30990171
schema:publication	IEEE Trans Biomed Eng
resource representing a document's body	covid:367fda3ef9ea317d3d0d5effbeba152f054cd4bd#body_text
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