About: Children are unlikely to have been the primary source of household SARS-CoV-2 infections

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Children are unlikely to have been the primary source of household SARS-CoV-2 infections
Creator	Lu, Jiahai Chew, Keng Short, Kirsty Bloxham, Conor Bowen, Asha Gilks, Charles Hulme, Katina Noye, Ellesandra Pickering, Janessa Sinclair, Jane Steele, Lauren Tong, Marcus Wei, Zhen Zhu, Yanshan
source	MedRxiv
abstract	BACKGROUND: Since its identification on the 7th of January 2020, SARS-CoV-2 has spread to more than 180 countries worldwide, causing >11,000 deaths. At present, viral disease and transmission amongst children is incompletely understood. Specifically, there is concern that children could be an important source of SARS-CoV-2 in household transmission clusters. METHODS: We performed an observational study analysing literature published between December 2019 and March 2020 of the clinical features of SARS-CoV-2 in children and descriptions of household transmission clusters of SARS-CoV-2. In these studies the index case of each cluster defined as the individual in the household cluster who first developed symptoms. FINDINGS: Drawing on studies from China, Singapore, South Korea, Japan, and Iran a broad range of clinical symptoms were observed in children. These ranged from asymptomatic to severe disease. Of the 31 household transmission clusters that were identified, 9.7% (3/31) were identified as having a paediatric index case. This is in contrast other zoonotic infections (namely H5N1 influenza virus) where 54% (30/56) of transmission clusters identified children as the index case. INTERPRETATION: Whilst SARS-CoV-2 can cause mild disease in children, the data available to date suggests that children have not played a substantive role in the intra-household transmission of SARS-CoV-2.
has issue date	2020-03-30(xsd:dateTime)
bibo:doi	10.1101/2020.03.26.20044826
has license	medrxiv
sha1sum (hex)	35c92a6f34bb8e02091454d2c55c1bc302c31eb7
schema:url	https://doi.org/10.1101/2020.03.26.20044826
resource representing a document's title	Children are unlikely to have been the primary source of household SARS-CoV-2 infections
resource representing a document's body	covid:35c92a6f34bb8e02091454d2c55c1bc302c31eb7#body_text
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