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About:
Psychological and Neurobiological Aspects of Suicide in Adolescents: Current Outlooks
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schema:ScholarlyArticle
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covidontheweb.inria.fr
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Type:
Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
has title
Psychological and Neurobiological Aspects of Suicide in Adolescents: Current Outlooks
Creator
Martin, S
Thompson, P
Behavior,
Brain,
Immunity -Health,
Castaneda, C
Chheda, S
Diaz-Pacheco, V
Gadad, B
Ghumman, U
Longhurst, M
Mangadu, T
Miranda-Arango, M
Vargas-Medrano, J
Source
Elsevier; Medline; PMC
abstract
Suicidality is one of the leading causes of death among young adults in the United States and represents a significant health problem worldwide. The suicide rate among adolescents in the United States has increased dramatically in the latest years and has been accompanied by considerable changes in youth suicide, especially among young girls. Henceforth, we need a good understanding of the risk factors contributing to suicidal behavior in youth. An explanatory model for suicidal behavior that links clinical and psychological risk factors to the underlying neurobiological, neuropsychological abnormalities related to suicidal behavior might predict to help identify treatment options and have empirical value. Our explanatory model proposes that developmental, biological factors (genetics, proteomics, epigenetics, immunological) and psychological or clinical (childhood adversities) may have causal relevance to the changes associated with suicidal behavior. In this way, our model integrates findings from several perspectives in suicidality and attempts to explain the relationship between various neurobiological, genetic, and clinical observations in suicide research, offering a comprehensive hypothesis to facilitate understanding of this complex outcome. Unraveling the knowledge of the complex interplay of psychological, biological, sociobiological, and clinical risk factors is highly essential, concerning the development of effective prevention strategy plans for suicidal ideation and suicide.
has issue date
2020-08-05
(
xsd:dateTime
)
bibo:doi
10.1016/j.bbih.2020.100124
bibo:pmid
32835300
has license
no-cc
sha1sum (hex)
33ae9bedfb41df0a2c1d6c0f662af3d7808bda6c
schema:url
https://doi.org/10.1016/j.bbih.2020.100124
resource representing a document's title
Psychological and Neurobiological Aspects of Suicide in Adolescents: Current Outlooks
has PubMed Central identifier
PMC7405877
has PubMed identifier
32835300
schema:publication
Brain Behav Immun Health
resource representing a document's body
covid:33ae9bedfb41df0a2c1d6c0f662af3d7808bda6c#body_text
is
schema:about
of
named entity 'youth suicide'
named entity 'Psychological'
named entity 'Journal'
named entity 'LATEST'
named entity 'United States'
named entity 'N-methyl-D-aspartic acid'
named entity 'suicidality'
named entity 'IFN-γ'
named entity 'school-based'
named entity 'DBT'
named entity 'gene'
named entity 'positive affect'
named entity 'inflammation'
named entity 'Prefrontal cortex'
named entity 'proteomics'
named entity 'committing suicide'
named entity 'suicide attempts'
named entity 'The suicide'
named entity 'Suicidality'
named entity 'young adults'
named entity 'allele'
named entity 'dopaminergic'
named entity 'suicidal ideation'
named entity 'allele'
named entity 'NE receptors'
named entity 'response to stress'
named entity 'polymorphism'
named entity 'suicidal behavior'
named entity 'CRHR1'
named entity 'Fearlessness'
named entity 'Problem-solving'
named entity 'anesthetic'
named entity 'protein'
named entity 'dopaminergic functioning'
named entity 'Pediatrics'
named entity 'mental health'
named entity 'suicide ideation'
named entity 'protective factor'
named entity 'Physical illness'
named entity 'case-control study'
named entity 'anxiety'
named entity '95%'
named entity 'prefrontal cortex'
named entity 'noradrenaline'
named entity 'cross-sectional'
named entity 'traumatic experiences'
named entity 'hormonal contraception'
named entity 'CRHR2'
named entity 'depression'
named entity 'L-DOPA'
named entity 'postmortem brain tissue'
named entity 'suicidal behavior'
named entity 'IL-6'
named entity 'Genetics'
named entity 'social distancing'
named entity 'insula'
named entity 'clinicalTrials.gov'
named entity 'PET'
named entity 'follow-up'
named entity 'psychopathology'
named entity 'impulsive behavior'
named entity 'midbrain'
named entity 'Structural neuroimaging'
named entity 'HPA'
named entity 'inflammatory cytokine'
named entity 'mRNA'
named entity '5-HT1a'
named entity 'family member'
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